Last reviewed · How we verify
L-cysteine
L-cysteine is an amino acid that has been studied for its potential to provide temporary relief for various symptoms such as nausea, diarrhea, and occasional headaches. It is not a primary treatment but can be used as a supportive measure. The drug's mechanism involves its role in antioxidant defense and detoxification processes, which may help alleviate some of these symptoms. However, it is important to note that L-cysteine is generally considered a dietary supplement rather than a pharmaceutical drug, and its use should be guided by healthcare professionals.
At a glance
| Generic name | L-cysteine |
|---|---|
| Also known as | amino acid |
| Sponsor | Louisiana State University Health Sciences Center Shreveport |
| Drug class | Amino acid derivative |
| Target | Cystine/glutamate transporter |
| Modality | Small molecule |
| Therapeutic area | Respiratory |
| Phase | FDA-approved |
Approved indications
- Amyloidosis
- Atelectasis due to Mucous Obstruction
- Bronchiectasis
- Bronchitis
- Contrast Media-Induced Nephrotoxicity Prevention
- Cystic fibrosis of the lung
- General anesthesia
- Poisoning by acetaminophen
- Thick Bronchial Secretions
Pipeline indications
Common side effects
- Mild transient diarrhea
- Itching
- Transitory exanthema
- Feeling of swelling of entire body
Serious adverse events
- Polycythemia vera
- Allergic sensitization
Key clinical trials
- Effects of NAC on Symptoms of CHR Patients (NA)
- Individualized Multiplex Pathophysiological Treatment of Severe Acute Infections: N-Acetylcysteine (PHASE4)
- Glutathione in Mild Cognitive Impairment (EARLY_PHASE1)
- A Study to Explore if Long-term Use of Mucinex Can Help With Symptoms in Patients With Stable Chronic Bronchitis. (PHASE4)
- Prospective Treatment Efficacy in IPF Using Genotype for Nac Selection (PRECISIONS) Trial (PHASE3)
- N-Acetylcysteine for Smoking Cessation in Tobacco and Cannabis Co-Use (PHASE4)
- A Clinical Trial Via Telepsychiatry of Treatments for the Management of Emotional Dysregulation in Youth (PHASE4)
- Comparative Clinical Study to Evaluate the Possible Efficacy and Safety of Oral N-Acetyl Cysteine Versus Rectal Diclofenac in the Prevention of Post Endoscopic Retrograde Cholangiopancreatography Pancreatitis (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |