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KX-826-(5%) BID

Suzhou Kintor Pharmaceutical Inc, · Phase 3 active Small molecule

KX-826 is a topical androgen receptor antagonist that inhibits DHT-mediated signaling in hair follicles to treat androgenetic alopecia.

KX-826 is a topical androgen receptor antagonist that inhibits DHT-mediated signaling in hair follicles to treat androgenetic alopecia. Used for Androgenetic alopecia (male pattern baldness).

At a glance

Generic nameKX-826-(5%) BID
Also known asKX-826-5 mg(5%)60mL BID
SponsorSuzhou Kintor Pharmaceutical Inc,
Drug classTopical androgen receptor antagonist
TargetAndrogen receptor (AR)
ModalitySmall molecule
Therapeutic areaDermatology
PhasePhase 3

Mechanism of action

KX-826 works by blocking the androgen receptor in dermal papilla cells and other hair follicle structures, preventing dihydrotestosterone (DHT) from triggering hair loss. By locally antagonizing androgen signaling without systemic absorption, it aims to halt hair miniaturization and promote hair growth while minimizing systemic side effects associated with oral antiandrogens.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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