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knee injection
Knee injections typically involve the administration of hyaluronic acid or corticosteroids to reduce pain and inflammation in the knee joint.
Knee injections typically involve the administration of hyaluronic acid or corticosteroids to reduce pain and inflammation in the knee joint. Used for Treatment of osteoarthritis pain in the knee.
At a glance
| Generic name | knee injection |
|---|---|
| Sponsor | OSF Healthcare System |
| Drug class | Corticosteroid or Hyaluronic acid |
| Modality | Small molecule |
| Therapeutic area | Musculoskeletal |
| Phase | Phase 3 |
Mechanism of action
Hyaluronic acid injections work by mimicking the natural lubricants found in healthy joints, reducing friction and inflammation. Corticosteroid injections, on the other hand, work by reducing inflammation and suppressing the immune system's response in the affected area.
Approved indications
- Treatment of osteoarthritis pain in the knee
Common side effects
- Joint pain
- Swelling
- Infection
Key clinical trials
- pAF for the Treatment of Osteoarthritis (PHASE1, PHASE2)
- Arthrosemid vs. Steroid for the Management Knee Osteoarthritis (PHASE4)
- The Effectiveness of BETY in Knee Osteoarthritis With Intra-Articular Injections (NA)
- A Study Evaluating the Safety, Tolerability, and Activity of ICM-203 in Subjects With Knee Osteoarthritis. (PHASE1, PHASE2)
- A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain. (PHASE3)
- Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain (PHASE3)
- A Study to Assess Safety and Tolerability of PCRX-201 in Subjects With Painful Osteoarthritis of the Knee (PHASE2)
- A Long-Term Safety and Efficacy Study of Lorecivivint in Subjects With Osteoarthritis of the Knee (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- knee injection CI brief — competitive landscape report
- knee injection updates RSS · CI watch RSS
- OSF Healthcare System portfolio CI