Last reviewed 2026-04-23 · How we verify

ketorolac eye drops

Ketorolac eye drops work by reducing inflammation and pain in the eye by inhibiting prostaglandin synthesis.

Ketorolac eye drops work by reducing inflammation and pain in the eye by inhibiting prostaglandin synthesis. Used for Ocular pain and inflammation.

At a glance

Mechanism of action

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that blocks the production of prostaglandins, which are hormone-like substances that cause pain and inflammation in the eye. By inhibiting prostaglandin synthesis, ketorolac eye drops reduce inflammation and pain in the eye, making it a useful treatment for conditions such as ocular pain and inflammation.

Approved indications

• Ocular pain and inflammation

Common side effects

• Eye irritation

Key clinical trials

• INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study (PHASE1)
• Evaluating a Dropless Postoperative Regimen After Cataract Surgery in a Vulnerable, County-hospital Population (PHASE4)
• Study of Complication Rates in Cataract Surgery Patients Treated With Combined Pre-operative NSAID, OMIDRIA, and Subconjunctival Triamcinolone Acetonide Compared With Peri-operative SOC (PHASE1, PHASE2)
• Effectiveness of Periocular Drug Injection in CATaract Surgery (PHASE3)
• Assessment of the Effects and Tolerability of RD03/2016 for the Treatment of Bacterial Conjunctivitis in Adults (PHASE2)
• The Laser in Pseudoexfoliation (LIP) Study (PHASE4)
• Ketorolac Levels in Vitreous and Aqueous Samples From Patients Undergoing Combined Cataract and Pars Plana Vitrectomy Surgeries With and Without Intracameral Phenylephrine 1.0% / Ketorolac 0.3% (EARLY_PHASE1)
• Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCT (PHASE4)

Primary sources

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