Last reviewed 2026-04-20 · How we verify

ketoconazole 400

At a glance

Approved indications

No approved indications tracked.

Common side effects

• "Fatigue (lethargy, malaise, asthenia)"
• Fatigue
• Hemoglobin
• fatigue
• Lymphopenia
• Rash/desquamation
• Musculoskeletal pain
• Nausea
• Hypocalcemia
• Decreased appetite
• Platelets
• Edema

Key clinical trials

• Neuro-pharmacological Properties of Repurposed Ketoconazole in Glioblastomas (EARLY_PHASE1)
• 177Lu Radiolabeled Monoclonal Antibody HuJ591 (177Lu-J591) and Ketoconazole in Patients With Prostate Cancer (PHASE2)
• RE-sensitizing With Supraphysiologic Testosterone to Overcome REsistance (The RESTORE Study) (PHASE2)
• Fenretinide/LXS Oral Powder Plus Ketoconazole in Recurrent Ovarian Cancer (PHASE1, PHASE2)
• Treating Patients With Prostate Cancer That Did Not Respond to Hormone Therapy (PHASE2)
• Buprenorphine Disposition and CYP3A (NA)
• ITT-5 Mechanisms of Spermatogenesis in Man (PHASE2)
• Influence of Ketoconazole on the Pharmacokinetics of Romidepsin in Patients With Advanced Cancer (PHASE1)

Primary sources

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