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JECEVAX
JECEVAX is a live attenuated Japanese encephalitis vaccine that stimulates immune responses against Japanese encephalitis virus.
JECEVAX is a live attenuated Japanese encephalitis vaccine that stimulates immune responses against Japanese encephalitis virus. Used for Prevention of Japanese encephalitis in endemic regions.
At a glance
| Generic name | JECEVAX |
|---|---|
| Sponsor | National Institute of Hygiene and Epidemiology, Vietnam |
| Drug class | Live attenuated vaccine |
| Target | Japanese encephalitis virus envelope proteins |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
JECEVAX contains a weakened form of Japanese encephalitis virus that triggers both humoral and cellular immune responses without causing disease. The vaccine primes the immune system to recognize and neutralize the virus upon natural exposure, providing protection against Japanese encephalitis infection.
Approved indications
- Prevention of Japanese encephalitis in endemic regions
Common side effects
- Local injection site reactions (pain, erythema, swelling)
- Fever
- Myalgia
- Headache
Key clinical trials
- Safety of Vero Cell - Derived Inactivated Japanese Encephalitis Vaccine (JECEVAX) in Children From 9-24 Months of Age (PHASE2)
- Evaluate Safety and Immunogenicity of a Vero Cell-Derived JE Vaccine in 9-24 Months of Age Children in Vietnam (PHASE3)
- Safety and Immunogenicity of JECEVAX in Young Children (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- JECEVAX CI brief — competitive landscape report
- JECEVAX updates RSS · CI watch RSS
- National Institute of Hygiene and Epidemiology, Vietnam portfolio CI