Last reviewed 2026-04-22 · How we verify

Irrisept (Irrigation Solution)

Irrisept is an irrigation solution designed to cleanse and irrigate wounds or surgical sites, likely containing antimicrobial or antiseptic agents to reduce infection risk.

Irrisept is an irrigation solution designed to cleanse and irrigate wounds or surgical sites, likely containing antimicrobial or antiseptic agents to reduce infection risk. Used for Wound irrigation and cleansing, Surgical site irrigation.

At a glance

Mechanism of action

As an irrigation solution, Irrisept is used to flush and clean tissue surfaces during medical procedures or wound care. The solution typically contains antimicrobial or antiseptic components that help reduce bacterial load and promote a clean surgical or wound environment, supporting healing and reducing infection risk.

Approved indications

• Wound irrigation and cleansing
• Surgical site irrigation

Common side effects

No common side effects on file.

Key clinical trials

• Effect of Antiseptic Irrigations With 0.05% Chlorhexidine Gluconate (Irrisept) Versus Normal Saline on Fasciocutaneous Flap-Based Closure of Pilonidal Disease (NA)
• Irrisept vs Traditional Antibiotic Irrigation for Virgin Penile Prosthesis Placement (PHASE3)
• Chlorhexidine Antiseptic Irrigation of the Bowel Segment During Radical Cystectomy and Urinary Diversion (NA)
• Irrisept in Emergency General Surgery Patients (PHASE4)
• Wound Irrigation With Saline Versus Hypodilute-chlorhexidine After Cesarean Section (WISHES Study) (NA)
• SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty (PHASE4)
• Irrisept Solution for Instrumented Spine Surgery (NA)
• Irrisept Spinal Fusion Pilot Study Protocol (NA)

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.