Last reviewed · How we verify
Iodine povidone
Povidone iodine is a broad-spectrum antimicrobial agent that releases iodine to disrupt microbial cell membranes and proteins, killing bacteria, viruses, fungi, and protozoa on contact.
Povidone iodine is a broad-spectrum antimicrobial agent that releases iodine to disrupt microbial cell membranes and proteins, killing bacteria, viruses, fungi, and protozoa on contact. Used for Skin antisepsis and disinfection, Wound cleansing and infection prevention, Surgical site preparation.
At a glance
| Generic name | Iodine povidone |
|---|---|
| Sponsor | Montefiore Medical Center |
| Drug class | Topical antiseptic/disinfectant |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease / Dermatology |
| Phase | FDA-approved |
Mechanism of action
Povidone iodine is a complex of iodine with polyvinylpyrrolidone (povidone) that acts as a topical antiseptic and disinfectant. The iodine component penetrates microbial cell walls and oxidizes essential proteins and nucleic acids, leading to rapid cell death. It is commonly used for skin antisepsis, wound disinfection, and prevention of infection in medical and surgical settings.
Approved indications
- Skin antisepsis and disinfection
- Wound cleansing and infection prevention
- Surgical site preparation
- Minor cuts, scrapes, and burns
Common side effects
- Local irritation or burning at application site
- Allergic contact dermatitis
- Iodine sensitivity reactions
Key clinical trials
- Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration
- Comparison of Pain Reduction in Painful Chronic Wounds With and Without Fat Grafting (NA)
- Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy (NA)
- Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder (NA)
- Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section (PHASE4)
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis (NA)
- Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Iodine povidone CI brief — competitive landscape report
- Iodine povidone updates RSS · CI watch RSS
- Montefiore Medical Center portfolio CI