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Iodine (Betadine)
Iodine (Betadine) is a broad-spectrum antimicrobial agent that kills microorganisms by oxidizing and disrupting their cellular proteins and nucleic acids.
Iodine (Betadine) is a broad-spectrum antimicrobial agent that kills microorganisms by oxidizing and disrupting their cellular proteins and nucleic acids. Used for Topical antisepsis and disinfection of skin wounds, Surgical site preparation, Prevention of infection in minor cuts and abrasions.
At a glance
| Generic name | Iodine (Betadine) |
|---|---|
| Sponsor | University of California, Los Angeles |
| Drug class | Topical antiseptic/disinfectant |
| Modality | Small molecule |
| Therapeutic area | Infectious Disease / Dermatology |
| Phase | Phase 3 |
Mechanism of action
Betadine is a povidone-iodine complex that releases iodine, which acts as a potent oxidizing agent. It denatures proteins and disrupts the cell membranes and DNA/RNA of bacteria, viruses, fungi, and other pathogens, making it effective as a topical antiseptic and disinfectant. The mechanism is non-selective and rapid, making it useful for wound preparation and infection prevention.
Approved indications
- Topical antisepsis and disinfection of skin wounds
- Surgical site preparation
- Prevention of infection in minor cuts and abrasions
Common side effects
- Skin irritation or sensitization
- Allergic contact dermatitis
- Iodine hypersensitivity reactions
Key clinical trials
- Durability of Three Monthly Loading Doses With Faricimab in Treatment-naïve Neovascular Age-related Macular Degeneration
- Comparison of Pain Reduction in Painful Chronic Wounds With and Without Fat Grafting (NA)
- Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy (NA)
- Efficacy of Autologous Conditioned Serum in Temporomandibular Joint Disorder (NA)
- Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section (PHASE4)
- CLinical Evaluation of ANtiseptic Skin Preparation in Revision Total Joint Arthroplasty of the Hip and Knee (NA)
- Povidone-Iodine Nasal Irrigation After Surgery for Chronic Rhinosinusitis (NA)
- Anterior Iliopsoas Space Block Versus PENG Block on Ease of Positioning for Spinal Anathesia in Patients Undergoing Hip Surgeries (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Iodine (Betadine) CI brief — competitive landscape report
- Iodine (Betadine) updates RSS · CI watch RSS
- University of California, Los Angeles portfolio CI