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Investigational COVID-19 Vaccine
Investigational COVID-19 Vaccine is a Not specified Biologic drug developed by BioNTech. It is currently FDA-approved for Prevention of COVID-19 in individuals 5 years of age and older, Prevention of COVID-19 in individuals 6 months through 4 years of age, Prevention of COVID-19 in individuals 12 years of age and older.
BioNTech's investigational COVID-19 vaccine is currently marketed for the prevention of COVID-19 in individuals aged 5 years and older. The vaccine holds a strong market position with key patent protection until 2028, providing a significant barrier to entry for generic competitors. However, the vaccine faces competition from Invivyd’s pemivibart and adintrevimab, which share similar antibody backbones and have demonstrated robust safety and efficacy in clinical trials.
At a glance
| Generic name | Investigational COVID-19 Vaccine |
|---|---|
| Sponsor | BioNTech |
| Drug class | Not specified |
| Target | Not specified |
| Modality | Biologic |
| Therapeutic area | Infectious Disease |
| Phase | FDA-approved |
Approved indications
- Prevention of COVID-19 in individuals 5 years of age and older
- Prevention of COVID-19 in individuals 6 months through 4 years of age
- Prevention of COVID-19 in individuals 12 years of age and older
- Prevention of COVID-19 in individuals 6 months through 4 years of age with certain health conditions
- Prevention of COVID-19 in individuals 5 years of age and older with certain health conditions
- Prevention of COVID-19 in individuals 12 years of age and older with certain health conditions
Common side effects
- Headache
- Injection site pain
- Fatigue
- Myalgia
- Chills
- Pyrexia
- Injection site pain (PAIN)
- Fatigue (FATIGUE)
- Headache (HEADACHE)
- Chills (CHILLS)
- Myalgia (MUSCLE PAIN)
- Arthralgia (JOINT PAIN)
Drug interactions
- Warfarin
- Immunosuppressants
- Live vaccines
- Interferon-alpha
- Interferon-gamma
- Corticosteroids
- Tofacitinib
- Upadacitinib
- Baricitinib
- Ruxolitinib
- Siponimod
- Ocrelizumab
Key clinical trials
- A Study on the Safety and Immune Response of Investigational mRNA Seasonal Flu/COVID-19 Combination Vaccine in Adults (PHASE1)
- A Study to Learn About How the Flu and COVID-19 Vaccines Act in Healthy People (PHASE1, PHASE2)
- Phase I Clinical Trial of GEN2-Recombinant COVID-19 Vaccine (CHO Cells) in Healthy People Aged 18 and Above (PHASE1)
- Safety and Effects of an Investigational COVID-19 Vaccine as Booster in Healthy People (PHASE1)
- A Study on the Immune Response and Safety of a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a COVID-19 mRNA Vaccine in Adults Aged 50 Years and Above (PHASE3)
- Covid-19 Vaccine Response in Elderly Subjects
- A Study of mRNA-based Influenza and SARS-CoV-2 (COVID-19) Multi-component Vaccines in Healthy Adults (PHASE1, PHASE2)
- A Study to Evaluate the Safety, Tolerability, and Immunogenicity of a Combined Modified RNA Vaccine Candidate Against COVID-19 and Influenza. (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Investigational COVID-19 Vaccine CI brief — competitive landscape report
- Investigational COVID-19 Vaccine updates RSS · CI watch RSS
- BioNTech portfolio CI
Frequently asked questions about Investigational COVID-19 Vaccine
What is Investigational COVID-19 Vaccine?
What is Investigational COVID-19 Vaccine used for?
Who makes Investigational COVID-19 Vaccine?
What drug class is Investigational COVID-19 Vaccine in?
What development phase is Investigational COVID-19 Vaccine in?
What are the side effects of Investigational COVID-19 Vaccine?
What does Investigational COVID-19 Vaccine target?
Related
- Drug class: All Not specified drugs
- Target: All drugs targeting Not specified
- Manufacturer: BioNTech — full pipeline
- Therapeutic area: All drugs in Infectious Disease
- Indication: Drugs for Prevention of COVID-19 in individuals 5 years of age and older
- Indication: Drugs for Prevention of COVID-19 in individuals 6 months through 4 years of age
- Indication: Drugs for Prevention of COVID-19 in individuals 12 years of age and older
- Compare: Investigational COVID-19 Vaccine vs similar drugs
- Pricing: Investigational COVID-19 Vaccine cost, discount & access