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Investigational aQIVc
Investigational aQIVc is a Influenza vaccine (quadrivalent, cell-based) Biologic drug developed by Seqirus. It is currently in Phase 3 development for Seasonal influenza prevention in adults.
aQIVc is a cell-based quadrivalent influenza vaccine designed to provide broader and more durable immune protection against multiple influenza strains.
aQIVc is a cell-based quadrivalent influenza vaccine designed to provide broader and more durable immune protection against multiple influenza strains. Used for Seasonal influenza prevention in adults.
At a glance
| Generic name | Investigational aQIVc |
|---|---|
| Sponsor | Seqirus |
| Drug class | Influenza vaccine (quadrivalent, cell-based) |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
aQIVc uses recombinant technology to produce influenza virus-like particles (VLPs) representing four influenza strains (H1N1, H3N2, and two B lineages) in cultured animal cells rather than eggs. This cell-based manufacturing approach may improve vaccine yield, reduce production time, and potentially enhance immunogenicity compared to traditional egg-based vaccines.
Approved indications
- Seasonal influenza prevention in adults
Common side effects
- Injection site pain or erythema
- Myalgia
- Headache
- Fatigue
Key clinical trials
- The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older (PHASE3)
- Safety and Immunogenicity of Different Formulations of an MF59-Adjuvanted Influenza Vaccine in Older Adults (PHASE2)
- Safety and Immunogenicity of Different Formulations of an MF59-Adjuvanted Influenza Vaccine in Older Adults ≥50 Years of Age (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Investigational aQIVc CI brief — competitive landscape report
- Investigational aQIVc updates RSS · CI watch RSS
- Seqirus portfolio CI
Frequently asked questions about Investigational aQIVc
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Related
- Drug class: All Influenza vaccine (quadrivalent, cell-based) drugs
- Manufacturer: Seqirus — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Seasonal influenza prevention in adults
- Compare: Investigational aQIVc vs similar drugs
- Pricing: Investigational aQIVc cost, discount & access