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Intravenous 0.9% Sodium Chloride
Intravenous 0.9% Sodium Chloride is a Crystalloid fluid / Electrolyte replacement solution Small molecule drug developed by GCP-Service International West GmbH. It is currently FDA-approved for Hypovolemia and dehydration, Perioperative fluid maintenance and replacement, Vehicle for intravenous drug administration. Also known as: Saline Infusion.
Intravenous 0.9% sodium chloride (normal saline) restores and maintains fluid and electrolyte balance by providing isotonic crystalloid replacement.
Intravenous 0.9% sodium chloride (normal saline) restores and maintains fluid and electrolyte balance by providing isotonic crystalloid replacement. Used for Hypovolemia and dehydration, Perioperative fluid maintenance and replacement, Vehicle for intravenous drug administration.
At a glance
| Generic name | Intravenous 0.9% Sodium Chloride |
|---|---|
| Also known as | Saline Infusion |
| Sponsor | GCP-Service International West GmbH |
| Drug class | Crystalloid fluid / Electrolyte replacement solution |
| Modality | Small molecule |
| Therapeutic area | Fluid and electrolyte management |
| Phase | FDA-approved |
Mechanism of action
Normal saline is a sterile solution containing 0.9% sodium chloride in water, formulated to match the osmolarity of blood plasma. It is administered intravenously to restore intravascular volume, maintain electrolyte homeostasis, and serve as a vehicle for drug delivery. It has no active pharmacological mechanism but functions as a physiological fluid replacement therapy.
Approved indications
- Hypovolemia and dehydration
- Perioperative fluid maintenance and replacement
- Vehicle for intravenous drug administration
- Electrolyte imbalance correction
Common side effects
- Hyperchloremic acidosis
- Fluid overload / pulmonary edema
- Hypernatremia
- Phlebitis at infusion site
Key clinical trials
- Magnesium Supplementation in Advanced Non-small Cell Lung Cancer (NSCLC) (PHASE2, PHASE3)
- Individual Response to Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Treatment of Peritoneal Carcinomatosis From Peritoneal Mesothelioma or Atypical Mesothelial Proliferation or From Ovarian, Colorectal, or Appendiceal Histologies (PHASE1)
- MAGNITUDE: A Phase 3 Study of NTLA-2001 in Participants With Transthyretin Amyloidosis With Cardiomyopathy (ATTR-CM) (PHASE3)
- Sphenopalatine Ganglion Block for Post-Dural Puncture Headache: A Pilot Randomised Controlled Trial (NA)
- Tocilizumab in Lung Transplantation (PHASE2)
- Improving Preterm Kidney Outcomes With Caffeine (PHASE2)
- Long-term Outcomes of Lidocaine Infusions for Post-Operative Pain (LOLIPOP) Trial (PHASE3)
- Bleeding Reduction in Acute and Chronic Kidney Patients Having Surgery (BRACKETS) Pilot Trial (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Intravenous 0.9% Sodium Chloride CI brief — competitive landscape report
- Intravenous 0.9% Sodium Chloride updates RSS · CI watch RSS
- GCP-Service International West GmbH portfolio CI
Frequently asked questions about Intravenous 0.9% Sodium Chloride
What is Intravenous 0.9% Sodium Chloride?
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Who makes Intravenous 0.9% Sodium Chloride?
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Related
- Drug class: All Crystalloid fluid / Electrolyte replacement solution drugs
- Manufacturer: GCP-Service International West GmbH — full pipeline
- Therapeutic area: All drugs in Fluid and electrolyte management
- Indication: Drugs for Hypovolemia and dehydration
- Indication: Drugs for Perioperative fluid maintenance and replacement
- Indication: Drugs for Vehicle for intravenous drug administration
- Also known as: Saline Infusion
- Compare: Intravenous 0.9% Sodium Chloride vs similar drugs
- Pricing: Intravenous 0.9% Sodium Chloride cost, discount & access