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Intranasal challenge drug
Intranasal challenge drug is a Small molecule drug developed by New York State Psychiatric Institute. It is currently in Phase 3 development for Psychiatric research and challenge testing (Phase 3 investigational use).
An intranasal challenge agent used to provoke or test physiological responses in psychiatric research settings.
An intranasal challenge agent used to provoke or test physiological responses in psychiatric research settings. Used for Psychiatric research and challenge testing (Phase 3 investigational use).
At a glance
| Generic name | Intranasal challenge drug |
|---|---|
| Sponsor | New York State Psychiatric Institute |
| Modality | Small molecule |
| Therapeutic area | Psychiatry |
| Phase | Phase 3 |
Mechanism of action
Intranasal challenge drugs are administered via nasal inhalation to induce acute neurobiological or behavioral responses in controlled research environments. These agents are typically used in Phase 3 psychiatric studies to model disease states, test treatment efficacy, or investigate underlying pathophysiology. The specific mechanism depends on the active agent, which is not identified in the available information.
Approved indications
- Psychiatric research and challenge testing (Phase 3 investigational use)
Common side effects
- Nasal irritation
- Transient anxiety or distress
- Headache
Key clinical trials
- A/Texas Flu Challenge (PHASE1)
- Re-challenge Immunotherapy With Cromolyn, TQB2102, and Panpulimab in Immune-Refractory Triple Negative Breast Cancer (PHASE2)
- GEneRating Mucosal Immunity After INfluenzA Infection and Vaccination in Lung and Lymphoid TissuE (NA)
- Is Brain Insulin Resistance a Feature of the Biology of Depression in Adolescents (NA)
- A Controlled Human Rhinovirus Infection Study of 2-Deoxy-D-Glucose in Healthy Adults (PHASE2)
- Factors Involved in Dymista's Superior Clinical Efficacy in the Treatment of Seasonal Allergic Rhinitis (PHASE4)
- Effects of Antipsychotics on Brain Insulin Action in Females (NA)
- Human Challenge Study to Evaluate the Efficacy of MV-012-968 Vaccine (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Intranasal challenge drug CI brief — competitive landscape report
- Intranasal challenge drug updates RSS · CI watch RSS
- New York State Psychiatric Institute portfolio CI
Frequently asked questions about Intranasal challenge drug
What is Intranasal challenge drug?
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Related
- Manufacturer: New York State Psychiatric Institute — full pipeline
- Therapeutic area: All drugs in Psychiatry
- Indication: Drugs for Psychiatric research and challenge testing (Phase 3 investigational use)
- Compare: Intranasal challenge drug vs similar drugs
- Pricing: Intranasal challenge drug cost, discount & access