Last reviewed · How we verify
Insulin Titration
Insulin titration is a dosing strategy that adjusts insulin administration based on blood glucose levels to achieve optimal glycemic control.
Insulin titration is a dosing strategy that adjusts insulin administration based on blood glucose levels to achieve optimal glycemic control. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus requiring insulin therapy.
At a glance
| Generic name | Insulin Titration |
|---|---|
| Also known as | Lantus, Levemir, Novolog, Lispro |
| Sponsor | Weill Medical College of Cornell University |
| Drug class | Insulin (dosing protocol) |
| Target | Insulin receptor |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | FDA-approved |
Mechanism of action
Insulin titration involves systematically increasing or decreasing insulin doses in response to measured blood glucose concentrations and patient metabolic needs. This approach aims to maintain target glucose ranges while minimizing hypoglycemia risk. It is a clinical management protocol rather than a novel drug entity.
Approved indications
- Type 2 diabetes mellitus requiring insulin therapy
Common side effects
- Hypoglycemia
- Weight gain
- Injection site reactions
Key clinical trials
- IMPACT-MACS: Adrenalectomy vs Semaglutide for Metabolic Outcomes in Mild Autonomous Cortisol Secretion (NA)
- Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes (PHASE2)
- iGlarLixi CGM Study in Chinese T2D Individuals After OADs (PHASE4)
- The Effect and Safety of a Novel CGM-Based Titration Algorithm for Basal Insulin in T2DM Participants. (NA)
- Comparing Pump With Subcutaneous Injection Delivery of PTH 1-34 in the Management of Chronic Hypoparathyroidism (PHASE2)
- A Pragmatic Randomized Trial to Evaluate the Comparative Effectiveness Between Dapagliflozin and Standard of Care in Type 2 Diabetes Patients (PHASE4)
- Automated Insulin Delivery (AID) for Basal Insulin Titration in Type 2 Diabetes (NA)
- Insulin Detemir in Obesity Management (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Insulin Titration CI brief — competitive landscape report
- Insulin Titration updates RSS · CI watch RSS
- Weill Medical College of Cornell University portfolio CI