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Insulin, regular - act rapid
Regular insulin binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels.
Regular insulin binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus (when oral agents are insufficient).
At a glance
| Generic name | Insulin, regular - act rapid |
|---|---|
| Sponsor | HaEmek Medical Center, Israel |
| Drug class | Insulin (short-acting) |
| Target | Insulin receptor |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | FDA-approved |
Mechanism of action
Regular insulin is a short-acting human insulin that mimics endogenous insulin secretion. It binds to insulin receptors on muscle, fat, and liver cells, facilitating glucose transport into cells and promoting glycogen synthesis while inhibiting gluconeogenesis. This results in rapid reduction of blood glucose levels, typically beginning within 30 minutes of injection.
Approved indications
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus (when oral agents are insufficient)
Common side effects
- Hypoglycemia
- Injection site reactions
- Lipodystrophy
- Weight gain
Key clinical trials
- Insulin in Treatment of Diabetes Mellitus With Pregnancy (NA)
- Basal Bolus vs. Sliding Scale for Treatment of Diabetic Patients in Medical Wards (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Insulin, regular - act rapid CI brief — competitive landscape report
- Insulin, regular - act rapid updates RSS · CI watch RSS
- HaEmek Medical Center, Israel portfolio CI