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insulin infusion
Insulin infusion delivers exogenous insulin directly into the bloodstream to regulate blood glucose by promoting cellular glucose uptake and storage.
Insulin infusion delivers exogenous insulin directly into the bloodstream to regulate blood glucose by promoting cellular glucose uptake and storage. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus (when oral agents are insufficient), Acute hyperglycemia in hospitalized patients.
At a glance
| Generic name | insulin infusion |
|---|---|
| Also known as | insuman rapid, Intravenous regular insulin infusion |
| Sponsor | IKFE Institute for Clinical Research and Development |
| Drug class | Insulin (recombinant human insulin or insulin analog) |
| Target | Insulin receptor (INSR) |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | FDA-approved |
Mechanism of action
Insulin infusion is a therapeutic delivery method for insulin, a hormone that binds to insulin receptors on cells to facilitate glucose uptake from the blood and promote glycogen synthesis and storage. This approach is used in acute care settings or for patients requiring continuous insulin delivery to maintain tight glycemic control. The infused insulin mimics the body's natural insulin secretion pattern to normalize blood glucose levels.
Approved indications
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus (when oral agents are insufficient)
- Acute hyperglycemia in hospitalized patients
- Diabetic ketoacidosis
Common side effects
- Hypoglycemia
- Injection site reactions
- Lipodystrophy
- Weight gain
Key clinical trials
- Text Message for Adolescents With Poorly Controlled Type 1 Diabetes (NA)
- Sleep Loss and Circadian Misalignment - Mechanisms of Insulin Resistance (PHASE4)
- Polycystic Ovary Syndrome in Type 1 Diabetes
- Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347) (NA)
- Glycemic Control After Antenatal Corticosteroids in Women With Pregestational and Gestational Diabetes (PHASE2)
- Glycemic Targets During CPB in Elderly Diabetes (NA)
- Intervention for Children With Type 1 Diabetes Targeting Gut Microbes (NA)
- The Importance of Insulin Action in the Brain for the Immune System During Physical Activity-Overweight (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- insulin infusion CI brief — competitive landscape report
- insulin infusion updates RSS · CI watch RSS
- IKFE Institute for Clinical Research and Development portfolio CI