Last reviewed · How we verify

insulin aspart + insulin aspart protamin

Steno Diabetes Center Copenhagen · FDA-approved active Small molecule

This is a biphasic insulin formulation combining rapid-acting insulin aspart with intermediate-acting insulin aspart protamine to provide both immediate and sustained blood glucose control.

This is a biphasic insulin formulation combining rapid-acting insulin aspart with intermediate-acting insulin aspart protamine to provide both immediate and sustained blood glucose control. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus.

At a glance

Generic nameinsulin aspart + insulin aspart protamin
Also known asnovomix
SponsorSteno Diabetes Center Copenhagen
Drug classInsulin (biphasic rapid-acting insulin analog)
TargetInsulin receptor
ModalitySmall molecule
Therapeutic areaDiabetes
PhaseFDA-approved

Mechanism of action

Insulin aspart is a rapid-acting insulin analog that binds to insulin receptors on muscle and fat cells, promoting glucose uptake and lowering blood glucose quickly. The protamine-complexed component provides a longer duration of action, creating a biphasic profile that mimics physiological insulin secretion with both mealtime and basal coverage in a single injection.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: