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Inactivated Poliovirus vaccine

Aga Khan University · FDA-approved active Biologic

Inactivated Poliovirus vaccine is a vaccine Biologic drug developed by Aga Khan University. It is currently FDA-approved for Prevention of poliomyelitis (polio) caused by poliovirus types 1, 2, and 3. Also known as: fractional dose Inactivated Poliovirus vaccine.

Inactivated poliovirus vaccine stimulates the immune system to produce antibodies against all three serotypes of poliovirus, providing protection against poliomyelitis infection.

Inactivated poliovirus vaccine stimulates the immune system to produce antibodies against all three serotypes of poliovirus, providing protection against poliomyelitis infection. Used for Prevention of poliomyelitis (polio) caused by poliovirus types 1, 2, and 3.

At a glance

Generic nameInactivated Poliovirus vaccine
Also known asfractional dose Inactivated Poliovirus vaccine
SponsorAga Khan University
Drug classvaccine
ModalityBiologic
Therapeutic areaImmunology
PhaseFDA-approved

Mechanism of action

The vaccine contains chemically inactivated (killed) poliovirus particles that cannot cause disease but retain immunogenicity. When administered, these inactivated viruses trigger both humoral (antibody) and cellular immune responses, leading to the production of neutralizing antibodies against poliovirus types 1, 2, and 3. This immune memory protects vaccinated individuals from infection if exposed to wild-type poliovirus.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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Frequently asked questions about Inactivated Poliovirus vaccine

What is Inactivated Poliovirus vaccine?

Inactivated Poliovirus vaccine is a vaccine drug developed by Aga Khan University, indicated for Prevention of poliomyelitis (polio) caused by poliovirus types 1, 2, and 3.

How does Inactivated Poliovirus vaccine work?

Inactivated poliovirus vaccine stimulates the immune system to produce antibodies against all three serotypes of poliovirus, providing protection against poliomyelitis infection.

What is Inactivated Poliovirus vaccine used for?

Inactivated Poliovirus vaccine is indicated for Prevention of poliomyelitis (polio) caused by poliovirus types 1, 2, and 3.

Who makes Inactivated Poliovirus vaccine?

Inactivated Poliovirus vaccine is developed and marketed by Aga Khan University (see full Aga Khan University pipeline at /company/aga-khan-university).

Is Inactivated Poliovirus vaccine also known as anything else?

Inactivated Poliovirus vaccine is also known as fractional dose Inactivated Poliovirus vaccine.

What drug class is Inactivated Poliovirus vaccine in?

Inactivated Poliovirus vaccine belongs to the vaccine class. See all vaccine drugs at /class/vaccine.

What development phase is Inactivated Poliovirus vaccine in?

Inactivated Poliovirus vaccine is FDA-approved (marketed).

What are the side effects of Inactivated Poliovirus vaccine?

Common side effects of Inactivated Poliovirus vaccine include Injection site pain, redness, or swelling, Fever, Irritability or fussiness, Fatigue.

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