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Icosapent (MND-2119)
Icosapent (MND-2119) is a Omega-3 fatty acid / Triglyceride-lowering agent Small molecule drug developed by Mochida Pharmaceutical Company, Ltd.. It is currently in Phase 3 development for Hypertriglyceridemia in patients with elevated cardiovascular risk.
Icosapent is a purified form of the omega-3 fatty acid eicosapentaenoic acid (EPA) that reduces triglycerides and modulates lipid metabolism.
Icosapent is a purified form of the omega-3 fatty acid eicosapentaenoic acid (EPA) that reduces triglycerides and modulates lipid metabolism. Used for Hypertriglyceridemia in patients with elevated cardiovascular risk.
At a glance
| Generic name | Icosapent (MND-2119) |
|---|---|
| Sponsor | Mochida Pharmaceutical Company, Ltd. |
| Drug class | Omega-3 fatty acid / Triglyceride-lowering agent |
| Target | Multiple lipid metabolism pathways; FFAR1 (GPR40), FFAR4 (GPR120) |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 3 |
Mechanism of action
Icosapent (EPA) works by increasing EPA levels in the bloodstream, which helps reduce triglyceride synthesis in the liver and promotes triglyceride clearance. It also has anti-inflammatory and antiplatelet properties that may contribute to cardiovascular benefits beyond simple triglyceride lowering.
Approved indications
- Hypertriglyceridemia in patients with elevated cardiovascular risk
Common side effects
- Bleeding or bruising
- Gastrointestinal upset
- Fishy aftertaste
Key clinical trials
- Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia (PHASE3)
- Efficacy of MND-2119 in Participants With Hypertriglyceridemia (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Icosapent (MND-2119) CI brief — competitive landscape report
- Icosapent (MND-2119) updates RSS · CI watch RSS
- Mochida Pharmaceutical Company, Ltd. portfolio CI
Frequently asked questions about Icosapent (MND-2119)
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Related
- Drug class: All Omega-3 fatty acid / Triglyceride-lowering agent drugs
- Target: All drugs targeting Multiple lipid metabolism pathways; FFAR1 (GPR40), FFAR4 (GPR120)
- Manufacturer: Mochida Pharmaceutical Company, Ltd. — full pipeline
- Therapeutic area: All drugs in Cardiovascular
- Indication: Drugs for Hypertriglyceridemia in patients with elevated cardiovascular risk
- Compare: Icosapent (MND-2119) vs similar drugs
- Pricing: Icosapent (MND-2119) cost, discount & access