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IBU TID
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever.
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that inhibits cyclooxygenase (COX) enzymes to reduce prostaglandin synthesis, thereby decreasing inflammation, pain, and fever. Used for Pain and inflammation (acute or chronic), Fever reduction, Rheumatoid arthritis.
At a glance
| Generic name | IBU TID |
|---|---|
| Sponsor | Pfizer |
| Drug class | Nonsteroidal anti-inflammatory drug (NSAID) |
| Target | COX-1, COX-2 |
| Modality | Small molecule |
| Therapeutic area | Pain Management, Inflammation |
| Phase | Phase 3 |
Mechanism of action
IBU TID (ibuprofen three times daily) works by blocking COX-1 and COX-2 enzymes, which are responsible for producing prostaglandins that mediate inflammatory responses and pain signaling. By reducing prostaglandin levels, the drug suppresses inflammation at the site of injury or disease and lowers pain perception and body temperature. The three-times-daily dosing regimen is a standard dosing schedule for ibuprofen in pain and inflammation management.
Approved indications
- Pain and inflammation (acute or chronic)
- Fever reduction
- Rheumatoid arthritis
- Osteoarthritis
Common side effects
- Gastrointestinal upset (nausea, dyspepsia, abdominal pain)
- Headache
- Dizziness
- Rash
- Increased cardiovascular risk (with chronic use)
- Renal impairment (with chronic use)
Key clinical trials
- Comparing Over the Counter Pain Medicines for Discomfort in Crohn's Disease (AVID-CD) (NA)
- ERAS (Enhanced Recovery After Surgery) and Multimodal Analgesia in Laparoscopic Cholecystectomy
- "Effect of Ibuprofen on Acute Inflammatory Response After One-Stage Periodontal Therapy" (PHASE4)
- Selected Exercise Program on Upper Cross Syndrome Post-unilateral Mastectomy (NA)
- Effect of Perioperative IV Ibuprofen on Cerebral Oxygenation and Postoperative Cognition During One-Lung Ventilation (NA)
- Psychosocial Factors and Postoperative Pain in Aesthetic Breast Surgery
- Aescin-Based Herbal Extract (Reparil) for Postoperative Sequelae After Mandibular Third Molar Surgery (NA)
- Modified Thoracoabdominal Nerve Plane Block In Laparoscopic Sleeve Gastrectomy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- IBU TID CI brief — competitive landscape report
- IBU TID updates RSS · CI watch RSS
- Pfizer portfolio CI