Last reviewed · How we verify
4-Hydroxyproline (hydroxyproline)
4-Hydroxyproline, also known as hydroxyproline, is a non-standard amino acid that plays a crucial role in collagen synthesis. It is a small molecule that works by incorporating into collagen chains, which are essential for skin, bone, and connective tissue health. However, as a non-drug entity, it does not have a specific target or approved indications. Hydroxyproline is not a patented or FDA-approved pharmaceutical, but rather a naturally occurring compound found in collagen. It is not associated with any specific commercial status or safety considerations.
At a glance
| Generic name | hydroxyproline |
|---|---|
| Therapeutic area | Bone |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- Evaluation of the Performance and Safety of a Linear Hyaluronic Acid-Based Medical Device in the Treatment of Surgical Wounds in the Oral Cavity. (NA)
- Metabolic Processes in Adults and Adolescents With Autism Spectrum Disorder (NA)
- Chronic Obstructive Pulmonary Disorder and Acute Exercise (NA)
- Oral Supplement and Acute Resistance Exercise (NA)
- Comparative Evaluation of Vitamin C and Injectable-platelet Rich Fibrin in the Management of Thin Gingival Phenotype (PHASE4)
- Ovarian Reserve and Matrix Metalloproteinases
- Topical Agents Containing Magnesium Sulfate & Wound Healing in the Rat Model (EARLY_PHASE1)
- Hydroxyproline Influence on Oxalate Metabolism (PHASE1,PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- 4-Hydroxyproline CI brief — competitive landscape report
- 4-Hydroxyproline updates RSS · CI watch RSS
- portfolio CI