🇺🇸 Hydrocodone-Acetaminophen in United States

8,172 US adverse-event reports

Safety signals — FAERS

Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.

• Window: 22 April 2025 – 22 April 2026
• Total reports: 8,172

Most-reported reactions

1. Chronic Kidney Disease — 1,074 reports (13.14%)
2. Fatigue — 900 reports (11.01%)
3. Drug Ineffective — 881 reports (10.78%)
4. Nausea — 857 reports (10.49%)
5. Completed Suicide — 856 reports (10.47%)
6. Acute Kidney Injury — 761 reports (9.31%)
7. Pain — 741 reports (9.07%)
8. Renal Failure — 720 reports (8.81%)
9. Diarrhoea — 716 reports (8.76%)
10. Death — 666 reports (8.15%)

Source database →

Frequently asked questions

Is Hydrocodone-Acetaminophen approved in United States?

Hydrocodone-Acetaminophen does not currently have US marketing authorisation in our dataset.

Who is the marketing authorisation holder for Hydrocodone-Acetaminophen in United States?

Henry Ford Health System is the originator. The local marketing authorisation holder may differ — check the official source linked above.