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hyaluronic acid 0.1%

University of Naples · FDA-approved active Small molecule

Hyaluronic acid acts as a humectant and viscoelastic agent that hydrates and lubricates tissues by binding water and forming a protective barrier.

Hyaluronic acid acts as a humectant and viscoelastic agent that hydrates and lubricates tissues by binding water and forming a protective barrier. Used for Dry skin conditions, Skin hydration and moisturization, Topical wound care and tissue protection.

At a glance

Generic namehyaluronic acid 0.1%
SponsorUniversity of Naples
Drug classHumectant/Viscoelastic agent
ModalitySmall molecule
Therapeutic areaDermatology
PhaseFDA-approved

Mechanism of action

Hyaluronic acid is a naturally occurring polysaccharide that binds large amounts of water, creating a hydrating and lubricating effect on skin and mucosal surfaces. At 0.1% concentration, it functions as a topical moisturizer and protective agent, reducing water loss from the stratum corneum and providing mechanical lubrication. This mechanism makes it useful for treating dry skin conditions and maintaining tissue hydration and comfort.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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