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Huminsulin Regular
Huminsulin Regular is a recombinant human insulin that binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels.
Huminsulin Regular is a recombinant human insulin that binds to insulin receptors on cells to promote glucose uptake and utilization, lowering blood glucose levels. Used for Type 1 diabetes mellitus, Type 2 diabetes mellitus.
At a glance
| Generic name | Huminsulin Regular |
|---|---|
| Also known as | Huminsulin Normal, LY041001 |
| Sponsor | Eli Lilly and Company |
| Drug class | Insulin, short-acting |
| Target | Insulin receptor |
| Modality | Small molecule |
| Therapeutic area | Diabetes |
| Phase | FDA-approved |
Mechanism of action
This is a short-acting insulin produced through recombinant DNA technology that mimics endogenous human insulin. It binds to insulin receptors on muscle, fat, and liver cells, facilitating glucose transport into these tissues and promoting glycogen synthesis while inhibiting gluconeogenesis. It is typically used for mealtime glucose control in diabetes management.
Approved indications
- Type 1 diabetes mellitus
- Type 2 diabetes mellitus
Common side effects
- Hypoglycemia
- Weight gain
- Injection site reactions
- Lipodystrophy
Key clinical trials
- Pharmacokinetic (PK) Bioequivalence and Pharmacodynamics (PD) of Julphar Insulin N and Huminsulin® Basal (PHASE1)
- A Trial to Investigate Post Prandial Blood Glucose Control With Fast-acting Human Insulin HinsBet® Compared to Insulin Lispro (Humalog®) and Regular Human Insulin (Huminsulin® Normal) After Ingestion of a Standardized Meal in Subjects With T1DM (PHASE1, PHASE2)
- 6-month Comparison of Morning Lantus Versus Neutral Protamine Hagedorn Insulin in Young Children With Type 1 Diabetes (PHASE3)
- A Study on the Effect of 2 Pen Devices on HbA1c (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |