Last reviewed · How we verify
High oxygenation target
High oxygenation target is a clinical protocol that increases inspired oxygen levels to maintain elevated blood oxygen saturation in hospitalized patients.
High oxygenation target is a clinical protocol that maintains elevated blood oxygen levels during patient care, rather than a traditional pharmaceutical drug. Used for Clinical protocol for oxygen management in hospitalized patients.
At a glance
| Generic name | High oxygenation target |
|---|---|
| Also known as | Inspired oxygen |
| Sponsor | Aalborg University Hospital |
| Modality | Small molecule |
| Therapeutic area | Critical Care / Perioperative Medicine |
| Phase | FDA-approved |
Mechanism of action
This is a therapeutic strategy rather than a traditional pharmaceutical drug, involving the administration of supplemental oxygen to achieve and maintain higher arterial oxygen partial pressure (PaO2) and oxygen saturation levels. The approach is based on the hypothesis that increased oxygen availability may improve tissue oxygenation and clinical outcomes in critically ill or acutely ill patients.
Approved indications
- Acute respiratory distress or hypoxemia in hospitalized patients
Common side effects
- Oxygen toxicity
- Absorption atelectasis
- Hyperoxia-related oxidative stress
Key clinical trials
- Development Of Neuroimaging Methods To Assess The Neurobiology Of Addiction (NA)
- Diaphragmatic Physiology Similarity Index May Titrate HFNC Flow Setting: A Prospective Observational Study (NA)
- THRIVE in Sedated Gastrointestinal Endoscopy
- HNFO With or Without Helmet NIV for Oxygenation Support in Acute Respiratory Failure Pilot RCT (NA)
- Acute Neurological Complications and Neurodevelopmental Outcome in Children Undergoing Extracorporeal Membrane Oxygenation.
- Combined Oscillation-Volume guarantEe Study (NA)
- Non-Invasive Ventilation Versus High-flow Nasal Oxygen in Intensive Care Units (NA)
- Intraoperative Multimodal Monitoring as a Means in Reducing the Duration of Mechanical Ventilation in High-Risk Patients Undergoing Major Abdominal Procedures - A Pilot Study (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- High oxygenation target CI brief — competitive landscape report
- High oxygenation target updates RSS · CI watch RSS
- Aalborg University Hospital portfolio CI