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HCP1102Placebo+HGP0711

Hanmi Pharmaceutical Company Limited · Phase 3 active Small molecule

HCP1102 is a dual GLP-1/GIP receptor agonist combined with HGP0711 (a GLP-1 receptor agonist) to enhance glucose control and weight loss through incretin mimicry.

HCP1102 is a dual GLP-1/GIP receptor agonist combined with HGP0711 (a GLP-1 receptor agonist) to enhance glucose control and weight loss through incretin mimicry. Used for Type 2 diabetes mellitus.

At a glance

Generic nameHCP1102Placebo+HGP0711
SponsorHanmi Pharmaceutical Company Limited
Drug classDual GLP-1/GIP receptor agonist
TargetGLP-1 receptor, GIP receptor
ModalitySmall molecule
Therapeutic areaEndocrinology / Diabetes
PhasePhase 3

Mechanism of action

This combination therapy activates both GLP-1 and GIP receptors, which stimulate insulin secretion in response to glucose, inhibit glucagon release, and promote satiety. The dual agonism provides synergistic effects on glycemic control and body weight reduction compared to single-agent GLP-1 agonists. The placebo control arm is used for comparative efficacy assessment in the phase 3 trial.

Approved indications

Common side effects

Key clinical trials

Primary sources

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SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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