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Gum Arabic
Gum Arabic is a Prebiotic fiber / dietary supplement Small molecule drug developed by University of Science and Technology, Yemen. It is currently FDA-approved for Chronic kidney disease (management of uremia and gut dysbiosis), Irritable bowel syndrome, General digestive health and prebiotic support. Also known as: Acacia Senegal.
Gum Arabic is a natural polysaccharide that acts as a prebiotic fiber, promoting the growth of beneficial gut bacteria and improving intestinal health.
Gum Arabic is a natural polysaccharide that acts as a prebiotic fiber, promoting the growth of beneficial gut bacteria and improving intestinal health. Used for Chronic kidney disease (management of uremia and gut dysbiosis), Irritable bowel syndrome, General digestive health and prebiotic support.
At a glance
| Generic name | Gum Arabic |
|---|---|
| Also known as | Acacia Senegal |
| Sponsor | University of Science and Technology, Yemen |
| Drug class | Prebiotic fiber / dietary supplement |
| Modality | Small molecule |
| Therapeutic area | Gastroenterology / Nutrition |
| Phase | FDA-approved |
Mechanism of action
Gum Arabic (acacia gum) is a soluble dietary fiber derived from the acacia tree that reaches the colon largely undigested. There it serves as a substrate for fermentation by commensal bacteria, selectively promoting the growth of beneficial microorganisms such as Bifidobacteria and Faecalibacterium prausnitzii. This prebiotic effect can improve gut barrier function, reduce inflammation, and modulate immune responses.
Approved indications
- Chronic kidney disease (management of uremia and gut dysbiosis)
- Irritable bowel syndrome
- General digestive health and prebiotic support
Common side effects
- Bloating
- Flatulence
- Abdominal discomfort
- Diarrhea
Key clinical trials
- The Role of Incorporating Acacia Gum in Foods on Glucose Homeostasis in Healthy Humans (NA)
- Effects of Gum Arabic on Metabolic Syndrome Parameters in Postmenopausal Women (PHASE2)
- Evaluation of the Impact of a Nutritional Formulation on Cognitive Performance Following Stress Exposure. (NA)
- Study With Two Coenzyme Q10 Products (NA)
- The Efficacy of Nutrilite All-plant Protein Booster to Improve Sarcopenia and Osteoarthritis in Middle-aged and Elderly People (NA)
- Fiber and Metformin Combination Therapy in Adolescents With Severe Obesity and Insulin Resistance (PHASE3)
- Effects of a Mushroom Blend on Gastrointestinal Symptoms and the Microbiome (NA)
- Non-inferiority RCT on Fish Waste-Derived vs. Synthetic Vitamin D Supplementation in Healthy Adults With Suboptimal Vitamin D Levels (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Gum Arabic CI brief — competitive landscape report
- Gum Arabic updates RSS · CI watch RSS
- University of Science and Technology, Yemen portfolio CI
Frequently asked questions about Gum Arabic
What is Gum Arabic?
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Related
- Drug class: All Prebiotic fiber / dietary supplement drugs
- Manufacturer: University of Science and Technology, Yemen — full pipeline
- Therapeutic area: All drugs in Gastroenterology / Nutrition
- Indication: Drugs for Chronic kidney disease (management of uremia and gut dysbiosis)
- Indication: Drugs for Irritable bowel syndrome
- Indication: Drugs for General digestive health and prebiotic support
- Also known as: Acacia Senegal
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing