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Guideline-directed therapy
Guideline-directed therapy is a Small molecule drug developed by St. Antonius Hospital. It is currently FDA-approved.
Guideline-directed therapy is used to treat various conditions, including Acute Heart Failure, Coronavirus Infection COVID-19, HER-2 Gene Amplification, Cancer, and Coronary Artery Disease. The therapy involves interventions such as goal-directed preload and afterload decrement, exposure to a "TOR" device, and exposure to a switched off "TOR" device, as studied in clinical trials like the Goal-Directed Afterload Reduction in Acute Congestive Cardiac Decompensation Study (GALACTIC).
At a glance
| Generic name | Guideline-directed therapy |
|---|---|
| Sponsor | St. Antonius Hospital |
| Modality | Small molecule |
| Phase | FDA-approved |
Approved indications
Common side effects
Key clinical trials
- HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer (EARLY_PHASE1)
- COronoary Microcirculation Analysis NETwork (NA)
- Sodium-Glucose Cotransporter 2 Inhibitor Use in a National Heart Failure Telemonitoring Program
- Telemedicine-Based Integrated Care for Heart Failure Prevention in Older Patients With Atrial Fibrillation (MIRACLE-AF III) (NA)
- Telemedicine-based Integrated Management of Atrial Fibrillation and Heart Failure in Older Patients in Village Clinics (NA)
- Educational Programs Based on Healthy Habits to Improve Quality of Life and Psychosocial Profile in Women With Neurodegenerative Diseases: the ADVICE Protocol Study (Phase 2) (NA)
- N-of-1 Trial to Promote Beta-Blocker Titration in Heart Failure (NA)
- Medication Withdrawal in Stable HF With Improved LVEF (PHASE2, PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Guideline-directed therapy CI brief — competitive landscape report
- Guideline-directed therapy updates RSS · CI watch RSS
- St. Antonius Hospital portfolio CI
Frequently asked questions about Guideline-directed therapy
What is Guideline-directed therapy?
Who makes Guideline-directed therapy?
What development phase is Guideline-directed therapy in?
Related
- Manufacturer: St. Antonius Hospital — full pipeline
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing