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GSK Biologicals' meningococcal vaccine GSK134612
GSK Biologicals' meningococcal vaccine GSK134612 is a Meningococcal vaccine Biologic drug developed by GlaxoSmithKline. It is currently in Phase 3 development for Prevention of invasive meningococcal disease.
GSK134612 is a meningococcal vaccine that stimulates the immune system to produce antibodies against multiple serogroups of Neisseria meningitidis.
GSK134612 is a meningococcal vaccine that stimulates the immune system to produce antibodies against multiple serogroups of Neisseria meningitidis. Used for Prevention of invasive meningococcal disease.
At a glance
| Generic name | GSK Biologicals' meningococcal vaccine GSK134612 |
|---|---|
| Sponsor | GlaxoSmithKline |
| Drug class | Meningococcal vaccine |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
The vaccine contains antigens from meningococcal serogroups designed to elicit both humoral and cellular immune responses. By priming the adaptive immune system against these bacterial pathogens, the vaccine provides protection against invasive meningococcal disease and meningitis caused by the targeted serogroups.
Approved indications
- Prevention of invasive meningococcal disease
Common side effects
- Injection site pain or erythema
- Fever
- Myalgia
- Fatigue
Key clinical trials
- Immunogenicity and Safety Study of 1 and 2 Doses of GlaxoSmithKline (GSK) Biologicals' Meningococcal Vaccine MenACWY-TT (GSK134612) in Toddlers, Persistence up to 5 Years After Vaccination and Co-administration With Pfizer's Prevenar 13™Vaccine (PHASE3)
- Study to Evaluate Persistence of Antibodies After Vaccination With Meningococcal Vaccine GSK134612 (PHASE3)
- Immunogenicity and Safety of Meningococcal Vaccine GSK 134612 Co-administered With Pneumococcal and DTPa-HBV-IPV/Hib Vaccines (PHASE3)
- Persistence and Booster Study of GSK Biologicals' Meningococcal Vaccine (GSK134612) in Healthy Children (PHASE3)
- Non-Inferiority of Meningococcal Vaccine GSK134612 Versus Mencevax™ in 2-10 Year Old Subjects (PHASE3)
- Safety & Immunogenicity Study of Meningococcal Vaccine GSK134612 Given With Priorix-Tetra™ to 12-23 Month-Old Children (PHASE3)
- Comparison of GSK Biologicals' Meningococcal Vaccine (GSK134612) and Licensed MenC-CRM197 Vaccine in Healthy Children (PHASE3)
- Study to Evaluate the Long-term Antibody Persistence of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine (GSK134612) Versus Mencevax ACWY in Healthy Adolescents and Adults and Booster Response to MenACWY-TT Vaccine Administered at 10 Years Post-primary Vaccination (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- GSK Biologicals' meningococcal vaccine GSK134612 CI brief — competitive landscape report
- GSK Biologicals' meningococcal vaccine GSK134612 updates RSS · CI watch RSS
- GlaxoSmithKline portfolio CI
Frequently asked questions about GSK Biologicals' meningococcal vaccine GSK134612
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Related
- Drug class: All Meningococcal vaccine drugs
- Manufacturer: GlaxoSmithKline — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Prevention of invasive meningococcal disease
- Compare: GSK Biologicals' meningococcal vaccine GSK134612 vs similar drugs
- Pricing: GSK Biologicals' meningococcal vaccine GSK134612 cost, discount & access