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GSK Biologicals' 208136, new formulation
GSK Biologicals' 208136, new formulation is a PD-1 inhibitor Biologic drug developed by GlaxoSmithKline. It is currently in Phase 2 development for Non-small cell lung cancer, PD-L1 positive, Head and neck squamous cell carcinoma.
This drug targets the PD-1 receptor to modulate the immune response.
This drug targets the PD-1 receptor to modulate the immune response. Used for Non-small cell lung cancer, PD-L1 positive, Head and neck squamous cell carcinoma.
At a glance
| Generic name | GSK Biologicals' 208136, new formulation |
|---|---|
| Sponsor | GlaxoSmithKline |
| Drug class | PD-1 inhibitor |
| Target | PD-1 |
| Modality | Biologic |
| Therapeutic area | Oncology |
| Phase | Phase 2 |
Mechanism of action
By binding to PD-1, it prevents the interaction with its ligands, PD-L1 and PD-L2, thereby releasing the brakes on T-cell activation and proliferation. This leads to enhanced anti-tumor immune responses.
Approved indications
- Non-small cell lung cancer, PD-L1 positive
- Head and neck squamous cell carcinoma
Common side effects
- Pneumonitis
- Hypothyroidism
- Diarrhea
- Fatigue
- Nausea
- Rash
- Pruritus
- Dry skin
- Itching
- Muscle pain
Key clinical trials
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- GSK Biologicals' 208136, new formulation CI brief — competitive landscape report
- GSK Biologicals' 208136, new formulation updates RSS · CI watch RSS
- GlaxoSmithKline portfolio CI
Frequently asked questions about GSK Biologicals' 208136, new formulation
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Related
- Drug class: All PD-1 inhibitor drugs
- Target: All drugs targeting PD-1
- Manufacturer: GlaxoSmithKline — full pipeline
- Therapeutic area: All drugs in Oncology
- Indication: Drugs for Non-small cell lung cancer, PD-L1 positive
- Indication: Drugs for Head and neck squamous cell carcinoma
- Compare: GSK Biologicals' 208136, new formulation vs similar drugs
- Pricing: GSK Biologicals' 208136, new formulation cost, discount & access