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green tea extract
Green tea extract contains polyphenols, primarily catechins and EGCG, which act as antioxidants and anti-inflammatory agents to reduce oxidative stress and cellular damage.
Green tea extract contains polyphenols, primarily catechins and EGCG, which act as antioxidants and anti-inflammatory agents to reduce oxidative stress and cellular damage. Used for Cancer prevention and adjunctive therapy (multiple cancer types), Cardiovascular health and metabolic support, General antioxidant and anti-inflammatory support.
At a glance
| Generic name | green tea extract |
|---|---|
| Also known as | Sunphenon 90LB, Epigallocatechin gallate, Polyphenol e, Sunphenon, EGCG (epigallocatechin gallate) |
| Sponsor | Centro Universitario de Ciencias de la Salud, Mexico |
| Drug class | Botanical extract / Polyphenol antioxidant |
| Modality | Small molecule |
| Therapeutic area | Oncology, Cardiovascular, Metabolic, General wellness |
| Phase | FDA-approved |
Mechanism of action
The active compounds in green tea extract, particularly epigallocatechin gallate (EGCG), scavenge free radicals and inhibit pro-inflammatory pathways. These polyphenols modulate multiple cellular signaling cascades involved in inflammation, apoptosis, and cell proliferation, contributing to potential protective effects across various disease states.
Approved indications
- Cancer prevention and adjunctive therapy (multiple cancer types)
- Cardiovascular health and metabolic support
- General antioxidant and anti-inflammatory support
Common side effects
- Gastrointestinal upset (nausea, dyspepsia)
- Hepatotoxicity (rare, at high doses)
- Caffeine-related effects (insomnia, anxiety)
Key clinical trials
- To Determine the Effect of Phaseolean on Glycemic Response to Carbohydrate Rich Meal in Healthy Adult Human Participants (NA)
- To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring (PHASE2)
- FRIEND: Fibroids and Unexplained Infertility Treatment With Epigallocatechin Gallate; A Natural CompounD in Green Tea (PHASE3)
- Beetroot Beverage and Repeated Sprint Power Output During RAST (NA)
- Monitoring of Early Disease Progression in Hereditary Transthyretin Amyloidosis
- Curcumin, Vitamin D and Green Tea in IBS-D (NA)
- A Clinical Trial to Investigate the Safety and Efficacy of Papillex® on Abnormal Cervical Cells Caused by HPV. (NA)
- A Study to See if an Energy Drink With Caffeine and Green Tea Increases Fat Burning When Exercising (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- green tea extract CI brief — competitive landscape report
- green tea extract updates RSS · CI watch RSS
- Centro Universitario de Ciencias de la Salud, Mexico portfolio CI