Last reviewed 2026-04-23 · How we verify

Grass pollen formulation

A grass pollen allergen extract that desensitizes the immune system to grass pollen allergens through repeated controlled exposure.

A grass pollen allergen extract that desensitizes the immune system to grass pollen allergens through repeated controlled exposure. Used for Grass pollen-induced allergic rhinitis, Grass pollen-induced allergic asthma.

At a glance

Mechanism of action

This immunotherapy formulation contains grass pollen allergens that are administered in gradually increasing doses to induce immune tolerance. Over time, this process shifts the immune response from IgE-mediated (allergic) to IgG-mediated (protective) antibodies and increases regulatory T cells, reducing allergic symptoms upon natural grass pollen exposure.

Approved indications

• Grass pollen-induced allergic rhinitis
• Grass pollen-induced allergic asthma

Common side effects

• Local injection site reactions (itching, swelling, erythema)
• Oral pruritus
• Mild systemic allergic reactions
• Anaphylaxis (rare)

Key clinical trials

• Intralymphatic Immunotherapy in Increasing Doses, Substudy (PHASE2, PHASE3)
• Safety and Efficacy Study of Intralymphatic Allergen-specific Immunotherapy (PHASE2, PHASE3)
• Safety and Efficacy of a Sublingual Specific Immunotherapy With an Extract of a Six Grass Pollen Mixture (PHASE3)

Primary sources

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Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

• Grass pollen formulation CI brief — competitive landscape report
• Grass pollen formulation updates RSS · CI watch RSS
• Allergopharma GmbH & Co. KG portfolio CI