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Grape Extract
Grape extract provides antioxidant and anti-inflammatory effects through polyphenols, particularly resveratrol and proanthocyanidins, which scavenge free radicals and modulate inflammatory pathways.
Grape extract provides antioxidant and anti-inflammatory effects through polyphenols, particularly resveratrol and proanthocyanidins, which scavenge free radicals and modulate inflammatory pathways. Used for Antioxidant support and general wellness, Cardiovascular health support.
At a glance
| Generic name | Grape Extract |
|---|---|
| Also known as | ShanStar Concord Grape |
| Sponsor | University of Mississippi Medical Center |
| Drug class | Botanical/Nutraceutical antioxidant |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular, Antioxidant/Anti-inflammatory |
| Phase | FDA-approved |
Mechanism of action
Grape extract contains high concentrations of polyphenolic compounds that act as antioxidants, neutralizing reactive oxygen species and reducing oxidative stress. These compounds also exhibit anti-inflammatory properties by inhibiting pro-inflammatory cytokine production and modulating signaling pathways involved in inflammation. The extract may also support vascular function and endothelial health through improved nitric oxide bioavailability.
Approved indications
- Antioxidant support and general wellness
- Cardiovascular health support
Common side effects
- Gastrointestinal upset
- Headache
- Dizziness
Key clinical trials
- Effectiveness of a Grape Seed Extract on Circulatory Measures in Healthy Adults (PHASE3)
- Study of Pharmacologic Manipulation of AGE (Advanced Glycation Endproducts) Levels in Prostate Cancer Patients Receiving Androgen Deprivation Therapy (PHASE2)
- Effect of Grapes in Inflammatory Bowel Disease (NA)
- Grape Polyphenols for Prevention of Chemotherapy-Induced Cardiotoxicity (NA)
- Leucoselect Phytosome for Neoadjuvant Treatment of Early Stage Lung Cancer (PHASE2)
- The Effect of Fermented Grape Juice Consumption on Fibromyalgia Patients (NA)
- Resveratrol Effects on Inflammatory Biomarkers and Cardiometabolic Parameters. (NA)
- Anthocyanin-Rich Table Grape Powder for Prophylaxis of Post-Operative Atrial Fibrillation (PHASE1, PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Grape Extract CI brief — competitive landscape report
- Grape Extract updates RSS · CI watch RSS
- University of Mississippi Medical Center portfolio CI