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glucosamine sulfate /chondroitin sulfate - capsules
glucosamine sulfate /chondroitin sulfate - capsules is a Nutraceutical/Dietary supplement Small molecule drug developed by Ache Laboratorios Farmaceuticos S.A.. It is currently in Phase 3 development for Osteoarthritis, particularly knee osteoarthritis.
Glucosamine sulfate and chondroitin sulfate work together to provide substrates for cartilage matrix synthesis and may reduce cartilage degradation in osteoarthritis.
Glucosamine sulfate and chondroitin sulfate work together to provide substrates for cartilage matrix synthesis and may reduce cartilage degradation in osteoarthritis. Used for Osteoarthritis, particularly knee osteoarthritis.
At a glance
| Generic name | glucosamine sulfate /chondroitin sulfate - capsules |
|---|---|
| Sponsor | Ache Laboratorios Farmaceuticos S.A. |
| Drug class | Nutraceutical/Dietary supplement |
| Modality | Small molecule |
| Therapeutic area | Rheumatology/Orthopedics |
| Phase | Phase 3 |
Mechanism of action
Glucosamine sulfate serves as a precursor for glycosaminoglycan synthesis, supporting cartilage structure and function. Chondroitin sulfate is a major component of cartilage extracellular matrix that may inhibit cartilage-degrading enzymes and promote water retention in cartilage. Together, these agents are proposed to slow cartilage loss and potentially promote cartilage repair in degenerative joint disease.
Approved indications
- Osteoarthritis, particularly knee osteoarthritis
Common side effects
- Gastrointestinal upset (nausea, dyspepsia, abdominal pain)
- Headache
- Allergic reactions (rare)
Key clinical trials
- A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis (NA)
- A Study to Assess Efficacy of Supporting Properties and Safety of ARTNEO in Patients With Knee Osteoarthritis (NA)
- To Evaluate the Efficacy and Safety of Collavant n2 in Individuals With Osteoarthritis of the Knee (NA)
- Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee (PHASE3)
- Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects (NA)
- Effect of Interventions on the Progression of Knee Osteoarthritis (PHASE4)
- Efficacy and Safety of Glucosamine Sulfate and Chondroitin Sulfate Combination in Treatment of Knee Osteoarthritis (PHASE3)
- Effectiveness of Glucosamine + Chondroitin in Osteoarthrosis (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- glucosamine sulfate /chondroitin sulfate - capsules CI brief — competitive landscape report
- glucosamine sulfate /chondroitin sulfate - capsules updates RSS · CI watch RSS
- Ache Laboratorios Farmaceuticos S.A. portfolio CI
Frequently asked questions about glucosamine sulfate /chondroitin sulfate - capsules
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Who makes glucosamine sulfate /chondroitin sulfate - capsules?
What drug class is glucosamine sulfate /chondroitin sulfate - capsules in?
What development phase is glucosamine sulfate /chondroitin sulfate - capsules in?
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Related
- Drug class: All Nutraceutical/Dietary supplement drugs
- Manufacturer: Ache Laboratorios Farmaceuticos S.A. — full pipeline
- Therapeutic area: All drugs in Rheumatology/Orthopedics
- Indication: Drugs for Osteoarthritis, particularly knee osteoarthritis
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