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Glucosamine/Chondroitin
Glucosamine and chondroitin are structural components of cartilage that may help maintain joint cartilage integrity and reduce cartilage degradation in osteoarthritis.
Glucosamine and chondroitin are structural components of cartilage that may help maintain joint cartilage integrity and reduce cartilage degradation in osteoarthritis. Used for Osteoarthritis pain and joint function.
At a glance
| Generic name | Glucosamine/Chondroitin |
|---|---|
| Sponsor | Indus Hospital and Health Network |
| Drug class | Dietary supplement / Nutraceutical |
| Modality | Small molecule |
| Therapeutic area | Rheumatology / Orthopedics |
| Phase | FDA-approved |
Mechanism of action
Glucosamine is an amino sugar that serves as a precursor for glycosaminoglycans and proteoglycans, key structural components of cartilage. Chondroitin is a glycosaminoglycan that helps cartilage retain water and resist compression. Together, they are proposed to slow cartilage breakdown and potentially stimulate cartilage repair, though clinical evidence for efficacy remains mixed.
Approved indications
- Osteoarthritis pain and joint function
Common side effects
- Gastrointestinal upset
- Nausea
- Headache
- Allergic reactions (rare)
Key clinical trials
- Validation of a French Version of the DHEQ (NA)
- A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis (NA)
- Combined Use of Potassium Nitrate Gel and Diode Laser for Dentin Hypersensitivity (NA)
- Long-Term Effects of Mobithron Advance on Knee Osteoarthritis Aims to Investigate the Effects of Mobithron Advance on OA Progression (EARLY_PHASE1)
- Effect of Fluoride Varnish Formulation on the Management of Dentin Hypersensitivity (NA)
- NT-II™ Collagen for Joint Discomfort and Function (NA)
- Biomimetic Hydroxyapatite Toothpaste and Mouthwash for Reducing Dental Sensitivity (NA)
- Effect of Crown Material on Gingival Microbial Colonization (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Glucosamine/Chondroitin CI brief — competitive landscape report
- Glucosamine/Chondroitin updates RSS · CI watch RSS
- Indus Hospital and Health Network portfolio CI