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GenTeal PM Night-Time

Joseph B. Ciolino, MD · FDA-approved active Small molecule

GenTeal PM Night-Time is an ocular lubricant that provides sustained moisture and protection to the cornea and conjunctiva during sleep.

GenTeal PM Night-Time is an ocular lubricant that provides sustained moisture and protection to the cornea and conjunctiva during sleep. Used for Dry eye disease, nighttime symptom relief, Corneal protection during sleep.

At a glance

Generic nameGenTeal PM Night-Time
Also known asGenTeal PM Night-Time Ophthalmic Ointment Alcon
SponsorJoseph B. Ciolino, MD
Drug classOcular lubricant / Artificial tear
ModalitySmall molecule
Therapeutic areaOphthalmology
PhaseFDA-approved

Mechanism of action

This product is a preservative-free artificial tear formulation designed for nighttime use in dry eye disease. It contains mineral oil and other lubricating agents that form a protective barrier on the ocular surface, reducing evaporation and providing extended comfort throughout the night. The night-time formulation is typically thicker and more occlusive than daytime versions to maintain hydration during extended eye closure.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

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