Last reviewed · How we verify

Gentamycin/citrate, Minocycline/EDTA

Henry Ford Health System · FDA-approved active Small molecule

This is a combination antimicrobial coating containing gentamicin (an aminoglycoside antibiotic) and minocycline (a tetracycline antibiotic) chelated with EDTA, designed to prevent bacterial biofilm formation and infection on medical devices.

This is a combination antimicrobial coating containing gentamicin (an aminoglycoside antibiotic) and minocycline (a tetracycline antibiotic) chelated with EDTA, designed to prevent bacterial biofilm formation and infection on medical devices. Used for Prevention of bacterial infection on medical devices (catheters, grafts, implants).

At a glance

Generic nameGentamycin/citrate, Minocycline/EDTA
SponsorHenry Ford Health System
Drug classAntimicrobial coating / combination antibiotic
ModalitySmall molecule
Therapeutic areaInfectious Disease / Medical Device Infection Prevention
PhaseFDA-approved

Mechanism of action

Gentamicin acts as a broad-spectrum bactericidal antibiotic that inhibits bacterial protein synthesis, while minocycline provides additional broad-spectrum coverage. EDTA (ethylenediaminetetraacetic acid) is a chelating agent that disrupts bacterial cell membranes and biofilm formation. Together, these agents are applied as a coating to medical devices to reduce infection risk.

Approved indications

Common side effects

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape: