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Gelatin sponge

Gelatin sponge is a hemostatic agent that absorbs blood and promotes clotting through physical absorption and platelet aggregation.

Gelatin sponge is a hemostatic agent that absorbs blood and promotes clotting through physical absorption and platelet aggregation. Used for Hemostasis in surgical procedures, Control of capillary, venous, and small arterial bleeding.

At a glance

Mechanism of action

Gelatin sponge is a porous, absorbable gelatin matrix derived from purified gelatin that functions as a hemostatic device. When placed in contact with bleeding surfaces, it absorbs blood and body fluids, which activates the coagulation cascade and promotes platelet aggregation and thrombus formation. The sponge is gradually absorbed by the body over 4-6 weeks as normal wound healing progresses.

Approved indications

• Hemostasis in surgical procedures
• Control of capillary, venous, and small arterial bleeding

Common side effects

• Infection at surgical site
• Abscess formation
• Foreign body reaction
• Delayed wound healing

Key clinical trials

• Clinical Comparison of Alb-PRF vs PRF on Postoperative Morbidity Following FGG Harvesting (NA)
• GATT-Patch Versus TachoSil in Liver Surgery (NA)
• Evaluation of the Effectiveness of Different Procedures on Palatinal Wound Healing After Free Gingival Graft Surgery. (NA)
• CECT Features of MVI Predict Response to TACE Plus TKI in Intermediate-stage HCC
• A-PRF and CGF in Palatal Donor Site Healing (PHASE2)
• Guided Bone Regeneration Using Ti-Reinforced PTFE Membrane Vs. Khoury's Technique in Augmentation of Posterior Mandibular Defects (NA)
• Short-term Embolization Using Gelatin Particles for FloW ModulAtion During Y90 Radioembolization (NA)
• Chitosan and i-PRF in Palatal Wound Healing (NA)

Primary sources

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