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Furosemide Topical Gel
Furosemide acts as a loop diuretic by inhibiting the sodium-potassium-chloride cotransporter in the ascending limb of the loop of Henle.
Furosemide acts as a loop diuretic by inhibiting the sodium-potassium-chloride cotransporter in the ascending limb of the loop of Henle. Used for Edema, Hypertension.
At a glance
| Generic name | Furosemide Topical Gel |
|---|---|
| Sponsor | Maruho Co., Ltd. |
| Drug class | Loop diuretic |
| Target | Sodium-potassium-chloride cotransporter |
| Modality | Small molecule |
| Therapeutic area | Cardiovascular |
| Phase | Phase 2 |
Mechanism of action
This inhibition leads to increased excretion of sodium, chloride, and water, resulting in a diuretic effect.
Approved indications
- Edema
- Hypertension
Common side effects
- Dehydration
- Electrolyte imbalance
- Hypokalemia
Key clinical trials
- A Study to Evaluate the Safety and Efficacy of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts (PHASE3)
- A Phase 3 Study to Evaluate the Efficacy and Safety of CLS006 Versus Vehicle in Subjects 2 Years of Age or Older With Cutaneous Common Warts (PHASE3)
- Topical Ionic Contra-Viral Therapy in Actinic Keratosis (PHASE2)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |