Last reviewed 2026-04-23 · How we verify

Furosemide 20 Milligrams

Furosemide inhibits sodium and chloride reabsorption in the ascending loop of Henle, promoting diuresis and reducing fluid volume.

Furosemide inhibits sodium and chloride reabsorption in the ascending loop of Henle, promoting diuresis and reducing fluid volume. Used for Edema associated with congestive heart failure, Edema associated with hepatic cirrhosis, Edema associated with renal disease.

At a glance

Mechanism of action

Furosemide is a loop diuretic that blocks the Na-K-2Cl cotransporter in the thick ascending limb of the loop of Henle, preventing reabsorption of sodium, potassium, and chloride. This increases urine output and reduces total body fluid volume, lowering blood pressure and reducing edema. It is one of the most potent diuretics available.

Approved indications

• Edema associated with congestive heart failure
• Edema associated with hepatic cirrhosis
• Edema associated with renal disease
• Hypertension
• Pulmonary edema

Common side effects

• Hypokalemia
• Hyperuricemia
• Ototoxicity
• Dehydration
• Hypotension
• Hyperglycemia

Key clinical trials

• Forced Diuresis After Flexible Ureteroscopy for Medium-Sized Renal Stones (NA)
• The Role of intraABDOminal Pressure and Point Of Care UltraSound to Guide Decongestive Therapy in Heart Failure (PHASE3)
• Furosemide for Accelerated Recovery of Blood Pressure Postpartum (PHASE2)
• The Del Nido Versus Cold Blood Cardioplegia in Aortic Valve Replacement (NA)

Primary sources

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