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Neomycin B (FRAMYCETIN)

Phase 3 active Small molecule ✓ Verified Jun 2026

Neomycin B (generic name: FRAMYCETIN) is a framycetin drug. It is currently in Phase 3 development.

Neomycin B works by blocking the transient receptor potential cation channel subfamily V member 1, which is involved in various cellular processes.

Neomycin B is a small molecule antibiotic with various clinical applications, including the treatment of conditions such as poliomyelitis, vaginitis, hordeolum, osteomyelitis, and cataract. It is used in experimental vaccines, including the Sabin Inactivated Poliovirus Vaccine, and has been studied for its safety and immunogenicity in adults, children, and infants.

Likelihood of approval
58.3% vs 58.3% industry baseline
If approved by FDA: likely 2028–2030
Steps remaining: NDA/BLA submission
Confidence: High
Why this estimate
  • Baseline phase 3 → approval rate +58.3pp
    Industry-wide phase 3 drugs reach approval ~58.3% of the time (BIO/Informa 2023 industry benchmark across all therapeutic areas).
Predicted approval windows by jurisdiction (conditional on FDA approval)
Regulator Country Likely year Lag vs FDA
FDA US 2028–2030
EMA EU 2029–2031 +0.7 yr
MHRA GB 2029–2031 +0.7 yr
Health Canada CA 2029–2032 +0.9 yr
TGA AU 2029–2032 +1.2 yr
PMDA JP 2029–2032 +1.5 yr
NMPA CN 2030–2033 +2.3 yr
MFDS KR 2029–2032 +1.4 yr
CDSCO IN 2029–2033 +1.8 yr
ANVISA BR 2030–2033 +2.3 yr

Hover any row for the lag rationale. Lag estimates are reduced when the drug has FDA Breakthrough or EMA PRIME designation (sponsors file globally in parallel).

Estimate based on the BIO/Informa industry phase transition rates plus per-drug modifiers for therapeutic area, sponsor type, FDA designations, mechanism, and trial design. Per-jurisdiction lags from Tufts CSDD international approval studies. Not investment, clinical or regulatory advice. Methodology: /methodology#likelihood.

At a glance

Generic nameFRAMYCETIN
Drug classframycetin
TargetLecithin retinol acyltransferase, Menin, Transient receptor potential cation channel subfamily V member 1
ModalitySmall molecule
Therapeutic areaOther
PhasePhase 3

Mechanism of action

Imagine your cells have special channels that help control the flow of important molecules. Neomycin B blocks these channels, which can help reduce inflammation and other symptoms. This can be beneficial for people with certain conditions, but it's essential to understand how it works and its potential effects on the body.

Approved indications

No approved indications tracked.

Common side effects

No common side effects on file.

Key clinical trials

Primary sources

Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.

SourceUsed for
ClinicalTrials.govTrial enrolment, design, endpoints, results

Competitive intelligence

For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:

Frequently asked questions about Neomycin B

What is Neomycin B?

Neomycin B (FRAMYCETIN) is a framycetin drug.

How does Neomycin B work?

Neomycin B works by blocking the transient receptor potential cation channel subfamily V member 1, which is involved in various cellular processes.

What is the generic name of Neomycin B?

FRAMYCETIN is the generic (nonproprietary) name of Neomycin B.

What drug class is Neomycin B in?

Neomycin B belongs to the framycetin class. See all framycetin drugs at /class/framycetin.

What development phase is Neomycin B in?

Neomycin B is in Phase 3.

What does Neomycin B target?

Neomycin B targets Lecithin retinol acyltransferase, Menin, Transient receptor potential cation channel subfamily V member 1 and is a framycetin.

Related

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing