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Fluticasone Propionate Cream 0.05%
Fluticasone Propionate Cream 0.05% is a Topical corticosteroid Small molecule drug developed by Netherlands Institute for Pigment Disorders. It is currently FDA-approved for Inflammatory and pruritic dermatoses responsive to topical corticosteroids, Eczema, psoriasis, and other inflammatory skin conditions.
Fluticasone propionate is a topical corticosteroid that suppresses local inflammatory and immune responses in the skin.
Fluticasone propionate is a topical corticosteroid that suppresses local inflammatory and immune responses in the skin. Used for Inflammatory and pruritic dermatoses responsive to topical corticosteroids, Eczema, psoriasis, and other inflammatory skin conditions.
At a glance
| Generic name | Fluticasone Propionate Cream 0.05% |
|---|---|
| Sponsor | Netherlands Institute for Pigment Disorders |
| Drug class | Topical corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Dermatology |
| Phase | FDA-approved |
Mechanism of action
Fluticasone propionate binds to glucocorticoid receptors in skin cells, inhibiting the production of pro-inflammatory cytokines and mediators. This reduces inflammation, itching, and erythema characteristic of inflammatory skin conditions. The 0.05% cream formulation provides moderate potency for localized dermatological use.
Approved indications
- Inflammatory and pruritic dermatoses responsive to topical corticosteroids
- Eczema, psoriasis, and other inflammatory skin conditions
Common side effects
- Skin atrophy
- Striae
- Telangiectasia
- Local irritation or burning
- Folliculitis
Key clinical trials
- Seal, Stopping Eczema and Allergy Study (PHASE2)
- Elocon vs Fluticasone in Localized Psoriasis (P03197) (PHASE4)
- Efficacy of Oral Supplementation of Probiotics in Children With Atopic Dermatitis (NA)
- Randomized Study to Compare the Bioequivalence of Two Fluticasone Propionate 0.05% Topical Creams
- A Randomized, Open-label, Comparative Study to Evaluate an Intermittent Dosing Regimen of Fluticasone Propionate 0.05% Cream (Twice Per Week) in Reducing the Risk of Relapse When Added to Regular Daily Moisturization Using PHYSIOGEL Lotion in Paediatric Subjects With Stabilized Atopic Dermatitis (PHASE4)
- Fractional Laser in Combination With UVB Therapy in Vitiligo Patients (NA)
- Efficacy Study of Topical Twice Weekly Fluticasone Treatment to Reduce Relapse in Atopic Dermatitis in Children (PHASE3)
- Effect of Fluticasone Proprionate 0.05% on Narrow Band UV-B in Active Vitiligo (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fluticasone Propionate Cream 0.05% CI brief — competitive landscape report
- Fluticasone Propionate Cream 0.05% updates RSS · CI watch RSS
- Netherlands Institute for Pigment Disorders portfolio CI
Frequently asked questions about Fluticasone Propionate Cream 0.05%
What is Fluticasone Propionate Cream 0.05%?
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Who makes Fluticasone Propionate Cream 0.05%?
What drug class is Fluticasone Propionate Cream 0.05% in?
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What does Fluticasone Propionate Cream 0.05% target?
Related
- Drug class: All Topical corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: Netherlands Institute for Pigment Disorders — full pipeline
- Therapeutic area: All drugs in Dermatology
- Indication: Drugs for Inflammatory and pruritic dermatoses responsive to topical corticosteroids
- Indication: Drugs for Eczema, psoriasis, and other inflammatory skin conditions
- Compare: Fluticasone Propionate Cream 0.05% vs similar drugs
- Pricing: Fluticasone Propionate Cream 0.05% cost, discount & access