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Fluticasone, Budesonide, Beclomethasone
Fluticasone, Budesonide, Beclomethasone is a Inhaled corticosteroid Small molecule drug developed by West Penn Allegheny Health System. It is currently FDA-approved for Asthma (maintenance and control), Chronic obstructive pulmonary disease (COPD), Allergic rhinitis (intranasal formulations). Also known as: Flovent Diskus, Pulmicort Flexhaler, QVAR.
These inhaled corticosteroids reduce airway inflammation by binding to glucocorticoid receptors and suppressing inflammatory cytokine production.
These inhaled corticosteroids reduce airway inflammation by binding to glucocorticoid receptors and suppressing inflammatory cytokine production. Used for Asthma (maintenance and control), Chronic obstructive pulmonary disease (COPD), Allergic rhinitis (intranasal formulations).
At a glance
| Generic name | Fluticasone, Budesonide, Beclomethasone |
|---|---|
| Also known as | Flovent Diskus, Pulmicort Flexhaler, QVAR |
| Sponsor | West Penn Allegheny Health System |
| Drug class | Inhaled corticosteroid |
| Target | Glucocorticoid receptor |
| Modality | Small molecule |
| Therapeutic area | Respiratory / Pulmonology |
| Phase | FDA-approved |
Mechanism of action
Fluticasone, budesonide, and beclomethasone are all inhaled corticosteroids that work by activating intracellular glucocorticoid receptors in airway epithelial and immune cells. This activation suppresses the production of pro-inflammatory mediators (cytokines, chemokines, adhesion molecules) and reduces recruitment of inflammatory cells to the airways. The result is decreased airway inflammation, mucus production, and bronchial hyperresponsiveness.
Approved indications
- Asthma (maintenance and control)
- Chronic obstructive pulmonary disease (COPD)
- Allergic rhinitis (intranasal formulations)
Common side effects
- Oropharyngeal candidiasis
- Dysphonia / hoarseness
- Tremor
- Headache
- Throat irritation
Key clinical trials
- Immuno-inflammatory Response of Erdosteine in COPD (NA)
- Individualizing Treatment for Asthma in Primary Care (Full Study) (PHASE4)
- Asthma Research in Children and Adolescents
- Acupuncture for Persistent Dyspnea Despite Medical Treatment in COPD (NA)
- Individualizing Treatment for Asthma in Primary Care (PHASE4)
- Periostin-guided Withdrawal of Inhaled Corticosteroids in Patients With Non-eosinophilic Asthma (PHASE4)
- CIVETTA: Correlating Inflammatory Values of FEno, SympToms, SpuTum and Lung Function in Asthma (PHASE2)
- Aclidinium Bromide Post-Authorisation Safety Study to Evaluate the Risk of Cardiovascular Endpoints
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fluticasone, Budesonide, Beclomethasone CI brief — competitive landscape report
- Fluticasone, Budesonide, Beclomethasone updates RSS · CI watch RSS
- West Penn Allegheny Health System portfolio CI
Frequently asked questions about Fluticasone, Budesonide, Beclomethasone
What is Fluticasone, Budesonide, Beclomethasone?
How does Fluticasone, Budesonide, Beclomethasone work?
What is Fluticasone, Budesonide, Beclomethasone used for?
Who makes Fluticasone, Budesonide, Beclomethasone?
Is Fluticasone, Budesonide, Beclomethasone also known as anything else?
What drug class is Fluticasone, Budesonide, Beclomethasone in?
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What are the side effects of Fluticasone, Budesonide, Beclomethasone?
What does Fluticasone, Budesonide, Beclomethasone target?
Related
- Drug class: All Inhaled corticosteroid drugs
- Target: All drugs targeting Glucocorticoid receptor
- Manufacturer: West Penn Allegheny Health System — full pipeline
- Therapeutic area: All drugs in Respiratory / Pulmonology
- Indication: Drugs for Asthma (maintenance and control)
- Indication: Drugs for Chronic obstructive pulmonary disease (COPD)
- Indication: Drugs for Allergic rhinitis (intranasal formulations)
- Also known as: Flovent Diskus, Pulmicort Flexhaler, QVAR
- Compare: Fluticasone, Budesonide, Beclomethasone vs similar drugs
- Pricing: Fluticasone, Budesonide, Beclomethasone cost, discount & access