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FluBlok Influenza Vaccination
FluBlok Influenza Vaccination is a Recombinant protein vaccine Biologic drug developed by Protein Sciences Corporation. It is currently in Phase 3 development for Prevention of influenza illness caused by influenza A and B viruses in adults 18 years of age and older. Also known as: FluBlok, rHA, rHA0, recombinant hemagglutinin.
FluBlok is a recombinant influenza vaccine that stimulates the immune system to produce antibodies against influenza virus surface proteins.
FluBlok is a recombinant influenza vaccine that stimulates the immune system to produce antibodies against influenza virus surface proteins. Used for Prevention of influenza illness caused by influenza A and B viruses in adults 18 years of age and older.
At a glance
| Generic name | FluBlok Influenza Vaccination |
|---|---|
| Also known as | FluBlok, rHA, rHA0, recombinant hemagglutinin |
| Sponsor | Protein Sciences Corporation |
| Drug class | Recombinant protein vaccine |
| Target | Influenza hemagglutinin (HA) |
| Modality | Biologic |
| Therapeutic area | Immunology / Infectious Disease |
| Phase | Phase 3 |
Mechanism of action
FluBlok uses recombinant DNA technology to produce hemagglutinin (HA) antigens from influenza virus strains without using eggs or live virus. The recombinant HA proteins are presented to the immune system to generate protective antibody responses against seasonal influenza strains. This approach allows for faster production and avoids potential issues associated with egg-based vaccine manufacturing.
Approved indications
- Prevention of influenza illness caused by influenza A and B viruses in adults 18 years of age and older
Common side effects
- Injection site soreness
- Headache
- Muscle aches
- Fatigue
- Low-grade fever
Key clinical trials
- Open-Label Influenza Vaccine Evaluation (NA)
- The Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (DRIVE III) Study (PHASE4)
- Immunogenicity Trial of 3 Influenza Vaccines (PHASE3)
- Immunogenicity of Influenza Vaccinations (PHASE4)
- Flublok v. Standard Dose Vaccine Effectiveness Among Kaiser Permanente Northern California Adults 18-64 Years
- Dynamics of the Immune Responses to Repeat Influenza Vaccination Exposures (PHASE4)
- Immunogenicity of Alternative Annual Influenza Vaccination Strategies in Older Adults in Hong Kong (PHASE4)
- Immunogenicity Trial of Recombinant Influenza Vaccine Among HCP in Israel (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- FluBlok Influenza Vaccination CI brief — competitive landscape report
- FluBlok Influenza Vaccination updates RSS · CI watch RSS
- Protein Sciences Corporation portfolio CI
Frequently asked questions about FluBlok Influenza Vaccination
What is FluBlok Influenza Vaccination?
How does FluBlok Influenza Vaccination work?
What is FluBlok Influenza Vaccination used for?
Who makes FluBlok Influenza Vaccination?
Is FluBlok Influenza Vaccination also known as anything else?
What drug class is FluBlok Influenza Vaccination in?
What development phase is FluBlok Influenza Vaccination in?
What are the side effects of FluBlok Influenza Vaccination?
What does FluBlok Influenza Vaccination target?
Related
- Drug class: All Recombinant protein vaccine drugs
- Target: All drugs targeting Influenza hemagglutinin (HA)
- Manufacturer: Protein Sciences Corporation — full pipeline
- Therapeutic area: All drugs in Immunology / Infectious Disease
- Indication: Drugs for Prevention of influenza illness caused by influenza A and B viruses in adults 18 years of age and older
- Also known as: FluBlok, rHA, rHA0, recombinant hemagglutinin
- Compare: FluBlok Influenza Vaccination vs similar drugs
- Pricing: FluBlok Influenza Vaccination cost, discount & access