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fixed combination latanoprost-timolol
fixed combination latanoprost-timolol is a Prostaglandin analog and beta-blocker combination Small molecule drug developed by Pfizer's Upjohn has merged with Mylan to form Viatris Inc.. It is currently in Phase 3 development for Glaucoma, Ocular hypertension.
Latanoprost-timolol is a fixed combination of a prostaglandin analog and a beta-blocker that works by reducing intraocular pressure in the eye.
Latanoprost-timolol is a fixed combination of a prostaglandin analog and a beta-blocker that works by reducing intraocular pressure in the eye. Used for Glaucoma, Ocular hypertension.
At a glance
| Generic name | fixed combination latanoprost-timolol |
|---|---|
| Sponsor | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. |
| Drug class | Prostaglandin analog and beta-blocker combination |
| Target | Beta-adrenergic receptors, Prostaglandin receptors |
| Modality | Small molecule |
| Therapeutic area | Ophthalmology |
| Phase | Phase 3 |
Mechanism of action
Latanoprost is a prostaglandin analog that increases the outflow of aqueous humor from the eye, while timolol is a beta-blocker that decreases the production of aqueous humor. This combination reduces intraocular pressure in patients with glaucoma or ocular hypertension.
Approved indications
- Glaucoma, Ocular hypertension
Common side effects
- Eye irritation
- Headache
- Dizziness
Key clinical trials
- Effect of IOP Lowering on Progressive HM (NA)
- Long Term Use Of Xalacom In Patients Glaucoma Or Ocular Hypertension
- Preservative-free Fixed-dose Combination of Tafluprost 0.0015% / Timolol 0.5% in Patients With Open-angle Glaucoma or Ocular Hypertension: Clinical Effectiveness, Tolerability and Safety in a Real World Setting
- 24-hour Efficacy and Tolerability of the Tafluprost-timolol Fixed Association Without Preservatives in Glaucomatous or Ocular Hypertensive Patients Already Treated With Latanoprost Preserved With BAK. A Prospective, Open Study of 3 Months Duration. (PHASE4)
- Switching From the Preserved to the Preservative - Free Latanoprost - Timolol FC in Glaucoma Patients With OSD (NA)
- Evaluation Of Intraocular Pressure Lowering-Effect Of Xalacom In Patients With Poag Or Oh. (PHASE4)
- A Study Demonstrating The Effect Of Latanoprost In Combination With Timolol, Latanoprost Alone And Timolol Alone On Eye Pressure In Open Angle Glaucoma Or Ocular Hypertension In Patients (PHASE3)
- A Study of Glaucoma or Ocular Hypertension in Patients Within the United States (PHASE3)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- fixed combination latanoprost-timolol CI brief — competitive landscape report
- fixed combination latanoprost-timolol updates RSS · CI watch RSS
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc. portfolio CI
Frequently asked questions about fixed combination latanoprost-timolol
What is fixed combination latanoprost-timolol?
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Related
- Drug class: All Prostaglandin analog and beta-blocker combination drugs
- Target: All drugs targeting Beta-adrenergic receptors, Prostaglandin receptors
- Manufacturer: Pfizer's Upjohn has merged with Mylan to form Viatris Inc. — full pipeline
- Therapeutic area: All drugs in Ophthalmology
- Indication: Drugs for Glaucoma, Ocular hypertension
- Compare: fixed combination latanoprost-timolol vs similar drugs
- Pricing: fixed combination latanoprost-timolol cost, discount & access