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Ferrous sulphate
Ferrous sulphate provides bioavailable iron to replenish depleted iron stores and restore hemoglobin synthesis.
Ferrous sulphate provides bioavailable iron to replenish depleted iron stores and restore hemoglobin synthesis. Used for Iron-deficiency anemia, Iron supplementation in pregnancy, Iron deficiency without anemia (prophylaxis).
At a glance
| Generic name | Ferrous sulphate |
|---|---|
| Also known as | Iron treatment, Ferrous sulphate treatment, Tardyferon, Robapharm, Fer |
| Sponsor | University of Lausanne |
| Drug class | Iron supplement |
| Target | Iron (Fe2+) for hemoglobin and myoglobin synthesis |
| Modality | Small molecule |
| Therapeutic area | Hematology |
| Phase | FDA-approved |
Mechanism of action
Ferrous sulphate is an iron supplement that delivers ferrous (Fe2+) iron, which is readily absorbed in the gastrointestinal tract. The absorbed iron is incorporated into hemoglobin and myoglobin, restoring oxygen-carrying capacity and correcting iron-deficiency anemia. It may also support iron-dependent enzymatic functions.
Approved indications
- Iron-deficiency anemia
- Iron supplementation in pregnancy
- Iron deficiency without anemia (prophylaxis)
Common side effects
- Gastrointestinal upset (nausea, abdominal discomfort)
- Constipation
- Dark stools
- Diarrhea
- Epigastric pain
Key clinical trials
- Iron and Immune Response to Vaccine (IRONMUM) (NA)
- Nano-Carbon Iron Suspension Injection Combined With Radiotherapy for Solid Tumors Phase II Clinical Trial (PHASE2)
- Iron Absorption and Losses in Young South African Women Living Without and With Overweight and Obesity (NA)
- Effectiveness and Acceptability of LISEFEX® (Liposomal Iron With Vitamin C and Fiber) in People With Iron Deficiency Anemia.
- Comparing High and Low Dose Iron Treatments for People on Peritoneal Dialysis: The PALaDIN Study (PHASE3)
- EFFECTS of MORINGA OLEIFERA LEAF POWDERS on HEMATOLOGICAL PROFILES IN PREGNANT WOMEN WITH IRON DEFICIENCY ANAEMIA (NA)
- Iron Absorption From IFA and MMS Supplements in Kenyan Women During the Second Trimester of Pregnancy (NA)
- The Role of Ferric Carboxymaltose in the Treatment of Pediatric Iron Deficiency Anemia in the Emergency Department (PHASE4)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |