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Ferrous sulfate + folic acid
Ferrous sulfate provides bioavailable iron to treat iron deficiency anemia, while folic acid (vitamin B9) supports red blood cell formation and DNA synthesis.
Ferrous sulfate provides bioavailable iron to treat iron deficiency anemia, while folic acid (vitamin B9) supports red blood cell formation and DNA synthesis. Used for Iron deficiency anemia, Folic acid deficiency anemia, Anemia prevention in pregnancy.
At a glance
| Generic name | Ferrous sulfate + folic acid |
|---|---|
| Also known as | Fefo, Iron Tablets |
| Sponsor | Ifakara Health Institute |
| Drug class | Nutritional supplement / hematologic agent |
| Modality | Small molecule |
| Therapeutic area | Hematology / Nutritional deficiency |
| Phase | FDA-approved |
Mechanism of action
Ferrous sulfate is an iron supplement that replenishes depleted iron stores, which are essential for hemoglobin synthesis and oxygen transport in red blood cells. Folic acid is a B vitamin cofactor required for nucleotide synthesis and cell division, particularly important in erythropoiesis. Together, they address two common nutritional deficiencies that contribute to anemia, particularly in populations at risk such as pregnant women and those in resource-limited settings.
Approved indications
- Iron deficiency anemia
- Folic acid deficiency anemia
- Anemia prevention in pregnancy
Common side effects
- Gastrointestinal upset (nausea, constipation, abdominal discomfort)
- Dark stools
- Metallic taste
- Headache
Key clinical trials
- EFFECTS of MORINGA OLEIFERA LEAF POWDERS on HEMATOLOGICAL PROFILES IN PREGNANT WOMEN WITH IRON DEFICIENCY ANAEMIA (NA)
- Iron Absorption From IFA and MMS Supplements in Kenyan Women During the Second Trimester of Pregnancy (NA)
- The Effect of Multiple Micronutrient Supplements in Reducing Anemia in Women of Reproductive Age (NA)
- Maternal Iron Deficiency and Childhood Health
- Aerobic Exercises on Persisted Post Burn Anemia (NA)
- Efficacy Evaluation of an ODF Iron Supplement Vs an Iron Supplement in Capsules in Subjects with Mild Anemia (NA)
- Prebiotic GOS and Lactoferrin With Iron Supplements (NA)
- Adiposity and Iron Requirements in Pregnancy (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Ferrous sulfate + folic acid CI brief — competitive landscape report
- Ferrous sulfate + folic acid updates RSS · CI watch RSS
- Ifakara Health Institute portfolio CI