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Fentanyl/Placebo injection
Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation.
Fentanyl is a synthetic opioid agonist that binds to mu-opioid receptors in the central nervous system to produce analgesia and sedation. Used for Acute pain management, Perioperative anesthesia and analgesia.
At a glance
| Generic name | Fentanyl/Placebo injection |
|---|---|
| Sponsor | University Hospital, Bordeaux |
| Drug class | Opioid analgesic |
| Target | Mu-opioid receptor (OPRM1) |
| Modality | Small molecule |
| Therapeutic area | Pain management / Anesthesia |
| Phase | FDA-approved |
Mechanism of action
Fentanyl activates mu-opioid receptors throughout the brain and spinal cord, inhibiting pain signal transmission and producing potent analgesic and sedative effects. It is approximately 50-100 times more potent than morphine. This formulation appears to be a research or clinical trial preparation comparing fentanyl to placebo, likely for pain management or anesthesia applications.
Approved indications
- Acute pain management
- Perioperative anesthesia and analgesia
Common side effects
- Respiratory depression
- Sedation
- Nausea
- Hypotension
- Bradycardia
- Pruritus
Key clinical trials
- Pain Reduction for Limb Injuries in Pediatric Emergency Departments: Intranasal Fentanyl or Intranasal Ketamine vs Oral Morphine (PHASE3)
- Safety and Efficacy of Dexmedetomidate vs. Midazolam for Procedural Sedation During Medical Thoracoscopy (PHASE3)
- Efficacy and Safety of Intrathecal Morphine for Postoperative Pain Management Following Planned Caesarean Section (PHASE4)
- Suprazygomatic Maxillary Nerve Block in Pediatric Tonsillectomy (NA)
- Comparison of the Efficiency of Femur Nerve Block and Intravenous Analgesia Treatment in Hip Fracture Patients (PHASE4)
- Pectoralis and Serratus Muscle Blocks (PHASE4)
- Intra Nasal Sufentanil Versus Intravenous Morphine for Acute Severe Traumatic Pain Analgesia in Emergency Setting (PHASE4)
- Comparison Between Intravenous Hydrocortisone and Ondansetron in Prevention of Post Spinal Anesthesia Hypotension (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- Fentanyl/Placebo injection CI brief — competitive landscape report
- Fentanyl/Placebo injection updates RSS · CI watch RSS
- University Hospital, Bordeaux portfolio CI