FDA authorised FENTANYL CITRATE on 11 July 1984 · 15,844 US adverse-event reports
Marketing authorisations
FDA — authorised 11 July 1984
Application: NDA019101
Marketing authorisation holder: HIKMA
Status: supplemented
FDA — authorised 12 January 1985
Application: NDA019115
Marketing authorisation holder: HOSPIRA
Status: supplemented
FDA — authorised 4 November 1998
Application: NDA020747
Marketing authorisation holder: CEPHALON
Status: supplemented
FDA — authorised 3 May 2019
Application: ANDA210762
Marketing authorisation holder: FRESENIUS KABI USA
Status: supplemented
FDA — authorised 1 September 2020
Application: ANDA212086
Marketing authorisation holder: FRESENIUS KABI USA
Status: supplemented
FDA
Status: approved
Safety signals — FAERS
Adverse reaction reports describe suspected side effects. A report does not mean the drug caused the event — co-medications, underlying disease and coincidence all contribute.
Window: 20 April 2025 – 20 April 2026
Total reports: 15,844
Most-reported reactions
Dependence — 3,936 reports (24.84%)
Overdose — 2,451 reports (15.47%)
Death — 2,071 reports (13.07%)
Drug Abuse — 1,727 reports (10.9%)
Toxicity To Various Agents — 1,414 reports (8.92%)