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EzPAP
EzPAP is a positive airway pressure device that delivers pressurized air to keep airways open during sleep.
EzPAP is a positive airway pressure device that delivers pressurized air to keep airways open during sleep. Used for Obstructive sleep apnea.
At a glance
| Generic name | EzPAP |
|---|---|
| Also known as | Positive Expiratory Pressure (PEP) |
| Sponsor | University of Colorado, Denver |
| Modality | Small molecule |
| Therapeutic area | Respiratory/Sleep Medicine |
| Phase | FDA-approved |
Mechanism of action
EzPAP functions as a non-invasive ventilation device designed to treat obstructive sleep apnea by delivering continuous or bilevel positive airway pressure to maintain patent airways during sleep. The device prevents airway collapse and hypoxic episodes characteristic of sleep apnea, improving sleep quality and reducing cardiovascular strain.
Approved indications
- Obstructive sleep apnea
Common side effects
- Nasal congestion
- Mask discomfort
- Dry mouth
- Claustrophobia
Key clinical trials
- Hyperinflation Respiratory Therapies in Cardiac Surgery Patients (NA)
- Comparison of the Effectiveness of Treatments in Carbon Monoxide Intoxications
- EzPAP Therapy Versus Non-invasive Ventilation Therapy
- Evaluation of Oxygen Delivery Methods in Acute Exacerbations of Chronic Obstructive Pulmonary Disease (COPD) (NA)
- Comparing the Effectiveness of Lung Expansion Therapy in Adult Human Subjects (NA)
- Pilot Evaluation Comparing Regional Distribution of Ventilation During Lung Expansion Therapy (NA)
- Positive Expiratory Pressure for the Treatment of Acute Asthma in Children (PHASE4)
- Interest of Positive Expiratory Pressure (PEP) Delivery by EzPAP® After Cardiac Surgery in the Management of Postoperative Atelectasis (NA)
Primary sources
Every claim on this page is sourced from regulatory or scientific primary sources. See our editorial policy for full methodology.
| Source | Used for |
|---|---|
| ClinicalTrials.gov | Trial enrolment, design, endpoints, results |
Competitive intelligence
For the full competitive landscape — auto-detected comparators, recent regulatory actions across the set, upcoming PDUFA, patent timeline, sponsor landscape:
- EzPAP CI brief — competitive landscape report
- EzPAP updates RSS · CI watch RSS
- University of Colorado, Denver portfolio CI